Recent updates on grading and classification of neuroendocrine tumors

JY Kim, SM Hong, JY Ro - Annals of diagnostic pathology, 2017 - Elsevier
Neuroendocrine tumors (NETs) are originating from neuroendocrine cells in diffuse
endocrine systems. NETs are diagnosed by characteristic histologic features and …

Recent updates on neuroendocrine tumors from the gastrointestinal and pancreatobiliary tracts

JY Kim, SM Hong - Archives of pathology & laboratory …, 2016 - meridian.allenpress.com
Context.—Gastrointestinal (GI) and pancreatobiliary tracts contain a variety of
neuroendocrine cells that constitute a diffuse endocrine system. Neuroendocrine tumors …

Alternative lengthening of telomeres and loss of DAXX/ATRX expression predicts metastatic disease and poor survival in patients with pancreatic neuroendocrine …

AD Singhi, TC Liu, JL Roncaioli, D Cao, HJ Zeh… - Clinical Cancer …, 2017 - AACR
Abstract Purpose: Pancreatic neuroendocrine tumors (PanNET) are a heterogeneous group
of neoplasms with increasing incidence and unpredictable behavior. Whole-exome …

[HTML][HTML] Somatostatin receptor expression related to TP53 and RB1 alterations in pancreatic and extrapancreatic neuroendocrine neoplasms with a Ki67-index above …

B Konukiewitz, AM Schlitter, M Jesinghaus, D Pfister… - Modern Pathology, 2017 - Elsevier
Somatostatin receptor 2A expression is a feature of well-differentiated neuroendocrine
neoplasms and is important for their diagnosis and therapy. Little is known about …

Neoplasms of the neuroendocrine pancreas: an update in the classification, definition, and molecular genetic advances

JM Guilmette, V Nosé - Advances in anatomic pathology, 2019 - journals.lww.com
This review focuses on discussing the main modifications of the recently published 2017
WHO Classification of Neoplasms of the Neuroendocrine Pancreas (panNEN). Recent …

Alternative lengthening of telomeres in primary pancreatic neuroendocrine tumors is associated with aggressive clinical behavior and poor survival

JY Kim, JA Brosnan-Cashman, S An, SJ Kim… - Clinical Cancer …, 2017 - AACR
Purpose: Alternative lengthening of telomeres (ALT), a telomerase-independent telomere
maintenance mechanism, is strongly associated with ATRX and DAXX alterations and …

Treatment response and outcomes of grade 3 pancreatic neuroendocrine neoplasms based on morphology: well differentiated versus poorly differentiated

N Raj, E Valentino, M Capanu, LH Tang, O Basturk… - Pancreas, 2017 - journals.lww.com
Objectives Emerging data suggest that not all grade 3 (G3) pancreatic neuroendocrine
neoplasms (panNENs) behave the same; tumor differentiation may predict outcome …

Treatment options for PNET liver metastases: a systematic review

G Nigri, N Petrucciani, T Debs, LM Mangogna… - World journal of surgical …, 2018 - Springer
Abstract Background Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic
neoplasms. About 40–80% of patients with PNET are metastatic at presentation, usually …

The spectrum of neuroendocrine tumors: histologic classification, unique features and areas of overlap

DS Klimstra, H Beltran, R Lilenbaum… - American Society of …, 2015 - ascopubs.org
Neuroendocrine neoplasms are diverse in terms of sites of origin, functional status, and
degrees of aggressiveness. This review will introduce some of the common features of …

High vimentin expression with E-cadherin expression loss predicts a poor prognosis after resection of grade 1 and 2 pancreatic neuroendocrine tumors

B Zhou, J Xiang, M Jin, X Zheng, G Li, S Yan - BMC cancer, 2021 - Springer
Background Pancreatic neuroendocrine tumors (pNETs) are a heterogeneous group of
neoplasms with malignant behaviors that can develop from inert slow growth or low …