[HTML][HTML] Unveiling the Roles of Cysteine Proteinases F and W: From Structure to Pathological Implications and Therapeutic Targets

K Zdravkova, O Mijanovic, A Brankovic, PM Ilicheva… - Cells, 2024 - mdpi.com
Cysteine cathepsins F and W are members of the papain-like cysteine protease family,
which have distinct structural features and functional roles in various physiological and …

Therapeutic cysteine protease inhibitors: a patent review (2018–present)

G Barchielli, A Capperucci, D Tanini - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Cysteine proteases are involved in a broad range of biological functions,
ranging from extracellular matrix turnover to immunity. Playing an important role in the onset …

An optimized AdaBoost algorithm with atherosclerosis diagnostic applications: adaptive weight-adjustable boosting

S Wang, W Liu, S Yang, H Huang - The Journal of Supercomputing, 2024 - Springer
In this study, a new boosting algorithm was proposed based on the traditional AdaBoost
algorithm to better address classification problems. While preserving the core idea of …

[HTML][HTML] The causal relationship between cathepsins and digestive system tumors: a Mendelian randomization study

X Huang, H Deng, B Zhang, K Wang, Y Qu, T Li… - Frontiers in …, 2024 - frontiersin.org
Background Multiple studies have confirmed the significant role of cathepsins in the
development and progression of digestive system tumors. However, further investigation is …

[HTML][HTML] Thyroid cancer prognostic biomarker ARL4A and its relationship with immune infiltration

X Han, J Liao, Y Zhou, X Hu, H Wu - International Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Thyroid cancer (THCA) is a prevalent form of cancer with high rates of
morbidity and mortality. The small GTPase ADP-ribosylation factor-like 4A (ARL4A) is …