Cryptococcus neoformans is an opportunistic fungal pathogen preferentially causing
disease in immunocompromised individuals such as organ-transplant-recipients, patients …

Background Paradoxical cryptococcosis-associated immune reconstitution inflammatory
syndrome (C-IRIS) affects~ 25% of human immunodeficiency virus (HIV)-infected patients …

Background: Community-acquired central nervous system infections (CA-CNS infections)
have the characteristics of acute onset and rapid progression, and are associated with high …

While type I conventional dendritic cells (cDC1s) are vital for generating adaptive immunity
against intracellular pathogens and tumors, their role in defense against fungal pathogen …

Acute infections of the intracranial central nervous system (CNS) often present as
neurological emergencies, where missed or delayed diagnosis and treatment can be …

Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal
infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic …

Cryptococcus gattii, an environmental yeast isolated from plants, is one of the agents of
cryptococcosis. Here, we aimed to develop a plant model to study C. gattii–plant interaction …

There is limited research into Invasive fungal disease (IFD) in children with no underlying
disease. We undertook a retrospective study of children with IFD who did not suffer from …

Voriconazole is a triazole antifungal used empirically for the treatment of complicated
meningitis associated with Cryptococcus neoformans. Biopsy studies show that the drug …

The fascinating and dangerous colored pathogens contain unique chemically pigmented
molecules, which give varied and efficient assistance as virulence factors to the crucial …