Hypervirulence and cross-resistance to a clinical antifungal are induced by an environmental fungicide in Cryptococcus gattii
HCS Carneiro, RW Bastos, NQ Ribeiro… - Science of the Total …, 2020 - Elsevier
The increasing human population requires ongoing efforts in food production. This is
frequently associated with an increased use of agrochemicals, leading to environmental …
frequently associated with an increased use of agrochemicals, leading to environmental …
[HTML][HTML] Sensitive LC-MS/MS methods for amphotericin B analysis in cerebrospinal fluid, plasma, plasma ultrafiltrate, and urine: application to clinical …
LF Pippa, MP Marques, ACT Silva, FC Vilar… - Frontiers in …, 2021 - frontiersin.org
Neurocryptococcosis, a meningoencephalitis caused by Cryptococcus spp, is treated with
amphotericin B (AmB) combined with fluconazole. The integrity of the brain-blood barrier …
amphotericin B (AmB) combined with fluconazole. The integrity of the brain-blood barrier …
Genome-wide association study identifies novel colony stimulating factor 1 locus conferring susceptibility to cryptococcosis in human immunodeficiency virus-infected …
S Kannambath, JN Jarvis, RM Wake… - Open Forum …, 2020 - academic.oup.com
Background Cryptococcus is the most common cause of meningitis in human
immunodeficiency virus (HIV)-infected Africans. Despite universal exposure, only 5%–10 …
immunodeficiency virus (HIV)-infected Africans. Despite universal exposure, only 5%–10 …
Cryptococcal infection in haematologic malignancies and haematopoietic stem cell transplantation
S Nematollahi, V Dioverti‐Prono - Mycoses, 2020 - Wiley Online Library
This review summarises both the recent and relevant studies about cryptococcal infections
in haematologic malignancies and haematopoietic stem cell transplantation. Although …
in haematologic malignancies and haematopoietic stem cell transplantation. Although …
Update on fungal infections of the central nervous system: emerging pathogens and emerging diagnostics
KC Bloch, SS Bailin - Current Opinion in Infectious Diseases, 2019 - journals.lww.com
Meningitis and brain abscess because of invasive fungal pathogens are frequently fatal
infections. Newer laboratory tests allowing antigen detection or molecular amplification from …
infections. Newer laboratory tests allowing antigen detection or molecular amplification from …
Analysis of the association of HLA subtypes with cryptococcal meningitis in HIV-negative immunocompetent patients
J Liu, H Wei, J Liu, L Peng, G Li, M Li, L Yang… - Future …, 2022 - Future Medicine
Objective: We aimed to study the possible relationship between cryptococcal meningitis
(CM) and HLA genotypes in HIV-negative immunocompetent patients. Methods: HLA loci of …
(CM) and HLA genotypes in HIV-negative immunocompetent patients. Methods: HLA loci of …
An Antivirulence approach for preventing Cryptococcus neoformans from crossing the blood-brain barrier via novel natural product inhibitors of a fungal …
PA Aaron, K Vu, A Gelli - MBio, 2020 - Am Soc Microbiol
Cryptococcus neoformans (Cn) is the leading cause of fungal meningitis, a deadly disease
with limited therapeutic options. Dissemination to the central nervous system hinges on the …
with limited therapeutic options. Dissemination to the central nervous system hinges on the …
Triple therapy combined with ventriculoperitoneal shunts can improve neurological function and shorten hospitalization time in non-HIV cryptococcal meningitis …
M Li, J Liu, X Deng, Q Gan, Y Wang, X Xu… - BMC Infectious …, 2020 - Springer
Background Raised intracranial pressure (ICP) and insufficient antifungal regimens are the
two main factors result to unsatisfactory outcomes in non-HIV cryptococcal meningitis (CM) …
two main factors result to unsatisfactory outcomes in non-HIV cryptococcal meningitis (CM) …
[HTML][HTML] Role of lipid transporters in fungal physiology and pathogenicity
J Rizzo, LD Stanchev, VKA da Silva… - Computational and …, 2019 - Elsevier
The fungal cell wall and membrane are the most common targets of antifungal agents, but
the potential of membrane lipid organization in regulating drug-target interactions has yet to …
the potential of membrane lipid organization in regulating drug-target interactions has yet to …
A nomogram for predicting paradoxical immune reconstitution inflammatory syndrome associated with cryptococcal meningitis among HIV-infected individuals in …
X Han, H Liu, Y Wang, P Wang, X Wang, Y Yi… - AIDS Research and …, 2022 - Springer
Background Cryptococcal meningitis (CM) associated immune reconstitution inflammatory
syndrome (CM-IRIS) is the second most common complication in HIV-infected individuals …
syndrome (CM-IRIS) is the second most common complication in HIV-infected individuals …