Treatment Options for Carbapenem-Resistant and Extensively Drug-Resistant Acinetobacter baumannii Infections

JA Viehman, MH Nguyen, Y Doi - Drugs, 2014 - Springer
Acinetobacter baumannii is a leading cause of healthcare-associated infections worldwide.
Because of various intrinsic and acquired mechanisms of resistance, most β-lactam agents …

Carbapenemase-producing Gram-negative bacteria: current epidemics, antimicrobial susceptibility and treatment options

SS Jean, WS Lee, C Lam, CW Hsu, RJ Chen… - Future …, 2015 - Taylor & Francis
Carbapenemases, with versatile hydrolytic capacity against β-lactams, are now an important
cause of resistance of Gram-negative bacteria. The genes encoding for the acquired …

Isolation of extensively drug resistant Acinetobacter baumannii from environmental surfaces inside intensive care units

Q Ababneh, S Abulaila, Z Jaradat - American Journal of Infection Control, 2022 - Elsevier
Background Acinetobacter baumannii is a nosocomial pathogen that has emerged as a
major threat in the health-care settings, particularly intensive care units (ICUs). The aim of …

Bloodstream infections caused by ST2 Acinetobacter baumannii: risk factors, antibiotic regimens, and virulence over 6 years period in China

K Yu, W Zeng, Y Xu, W Liao, W Xu, T Zhou… - … Resistance & Infection …, 2021 - Springer
Background Bloodstream infection (BSI) caused by multidrug-resistant Acinetobacter
baumannii (MDR-AB) has been increasingly observed among hospitalized patients. The …

Molecular Epidemiology and Mechanisms of Carbapenem Resistance of Acinetobacter spp. in Asia and Oceania

W Kamolvit, HE Sidjabat, DL Paterson - Microbial Drug Resistance, 2015 - liebertpub.com
Acinetobacter baumannii is emerging as a pathogen that is commonly involved in
nosocomial infections. A. baumannii has exhibited the ability to develop multidrug resistance …

Prevalence of different carbapenemase genes among carbapenem-resistant Acinetobacter baumannii blood isolates in Taiwan

TH Wang, YS Leu, NY Wang, CP Liu… - Antimicrobial Resistance & …, 2018 - Springer
Background Although the prevalence of the carbapenem-resistant A. baumannii (CRAB) has
increased in Taiwan, few studies have elucidated the prevalence of different …

A Prospective Study of Acinetobacter baumannii Complex Isolates and Colistin Susceptibility Monitoring by Mass Spectrometry of Microbial Membrane Glycolipids

LM Leung, CL McElheny, FM Gardner… - Journal of clinical …, 2019 - Am Soc Microbiol
Acinetobacter baumannii is a prevalent nosocomial pathogen with a high incidence of
multidrug resistance. Treatment of infections due to this organism with colistin, a last-resort …

[HTML][HTML] Comparison of the clinical efficacy between tigecycline plus extended-infusion imipenem and sulbactam plus imipenem against ventilator-associated …

SS Jean, TC Hsieh, CW Hsu, WS Lee, KJ Bai… - Journal of Microbiology …, 2016 - Elsevier
Abstract Background/Purpose To compare the clinical efficacy between salvage
antimicrobial regimen consisting of tigecycline plus extended-infusion imipenem/cilastatin …

Acinetobacter baumannii Infections in Hospitalized Patients, Treatment Outcomes

D Alrahmany, AF Omar, G Harb, WS El Nekidy… - Antibiotics, 2021 - mdpi.com
Background Acinetobacter baumannii (AB), an opportunistic pathogen, could develop into
serious infections with high mortality and financial burden. The debate surrounding the …

Evaluation of Fosfomycin-Sulbactam Combination Therapy against Carbapenem-Resistant Acinetobacter baumannii Isolates in a Hollow-Fibre Infection Model

S Mohd Sazlly Lim, A Heffernan, S Naicker, S Wallis… - Antibiotics, 2022 - mdpi.com
Static concentration in vitro studies have demonstrated that fosfomycin-or sulbactam-based
combinations may be efficacious against carbapenem-resistant Acinetobacter baumannii …