2. Methods Based on the GRADE workflow, the Guidelines Committee of ECCO [GuiCom]
selected a panel of 48 experts supported by a team of methodologists and librarians …

Background Biomarkers of intestinal inflammation, such as faecal calprotectin and C-
reactive protein, have been recommended for monitoring patients with Crohn's disease, but …

Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are
chronic, progressive, immune-mediated diseases of adults and children that have no cure …

Therapeutic drug monitoring (TDM) of biologics is a rapidly evolving field. We aimed to
provide a consensus statement regarding the clinical utility of TDM for biologics in …

This article is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's …

The cost of caring for patients with inflammatory bowel disease (IBD) continues to increase
worldwide. The cause is not only a steady increase in the prevalence of Crohn's disease …

Objective Increasing evidence supports reciprocal communication between the enteric and
the central nervous system in disease, termed the 'gut–brain axis'. Recent findings suggest a …

There are several scoring systems presently available to classify disease severity in
ulcerative colitis [UC] within the multiple domains of disease activity, which aid objective …

Background & Aims Therapeutic drug monitoring (TDM) is widely available for biologic
therapies in patients with inflammatory bowel disease (IBD). We reviewed current data and …

Abstract Background and Aims Management of Crohn's disease and ulcerative colitis has
typically relied upon treatment intensification driven by symptoms alone. However, a 'treat-to …