Electrospun fiber‐based immune engineering in regenerative medicine

Y Xu, Q Saiding, X Zhou, J Wang, W Cui… - Smart Medicine, 2024 - Wiley Online Library
Immune engineering, a burgeoning field within regenerative medicine, involves a spectrum
of strategies to optimize the intricate interplay between tissue regenerative biomaterials and …

[HTML][HTML] A review of abdominal meshes for hernia repair—Current status and emerging solutions

A Najm, AG Niculescu, BS Gaspar, AM Grumezescu… - Materials, 2023 - mdpi.com
Abdominal hernias are common issues in the clinical setting, burdening millions of patients
worldwide. Associated with pain, decreased quality of life, and severe potential …

[HTML][HTML] Killing two birds with one stone: A therapeutic copper-loaded bio-patch promoted abdominal wall repair via VEGF pathway

N Zhang, Y Huang, P Wei, L Sun, W Jing, Y Xue… - Materials Today Bio, 2023 - Elsevier
Hernia and life-threatening intestinal obstruction often result from abdominal wall injuries,
and the regeneration of abdominal wall defects is limited due to the lack of biocompatible …

A Bio‐Inspired Janus Patch for Treating Abdominal Wall Defects

Z Liu, J Liu, Y Bai, S Wu, J Zhao… - Advanced Functional …, 2024 - Wiley Online Library
Implantable biomedical patch used in treating abdominal wall defects requires antibacterial,
anti‐adhesion, and pro‐healing activities to ensure surgical success and prevent …

Zwitterion mediated anti-protein adsorption on polypropylene mesh to reduce inflammation for efficient hernia repair

Y Mao, Q Wang, H Zhang, Y Li, L Wang - Biomaterials Advances, 2024 - Elsevier
The effectiveness of polypropylene (PP) mesh is often compromised by severe inflammation.
Engineering anti-inflammatory coatings has significant implications for PP mesh to repair …

[HTML][HTML] Asymmetric porous composite hydrogel patch for microenvironment-adapted repair of contaminated abdominal wall defects

Y Yu, Y Tang, W Liang, Y Wang, Y Ouyang… - Engineered …, 2024 - Elsevier
Effective antibacterial property and long-term mechanical support are essential for the repair
of complex abdominal wall defects associated with infection. However, clinically available …

Spider-Silk-like Fiber Mat-Covered Polypropylene Warp-Knitted Hernia Mesh for Inhibition of Fibrosis under Dynamic Environment

Y Jiao, X Yang, Y Li, F Wang, L Wang, C Li - Biomacromolecules, 2024 - ACS Publications
Hernia surgery is a widely performed procedure, and the use of a polypropylene mesh is
considered the standard approach. However, the mesh often leads to complications …

Unlocking the biological response of smart Stimuli-Responsive hydrogels and their application in biological systems

M Kumi, O Ejeromedoghene, WD Sudane… - European Polymer …, 2024 - Elsevier
The capacity of materials to detect and adapt to environmental changes has long fascinated
researchers, leading to the development of smart materials. These materials, particularly …

[HTML][HTML] Novel Material Optimization Strategies for Developing Upgraded Abdominal Meshes

A Najm, AG Niculescu, M Rădulescu… - International Journal of …, 2023 - mdpi.com
Over 20 million hernias are operated on globally per year, with most interventions requiring
mesh reinforcement. A wide range of such medical devices are currently available on the …

Therapeutic nucleic acids in regenerative medicine and tissue repair

Q Saiding, D Qin, S An, DN Patel, MM Khan, N Kong… - Nano Research, 2024 - Springer
In the vanguard of biomedical innovation, regenerative medicine emerges as a
transformative paradigm, concentrating its efforts on rectifying tissue deficits and functional …