Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Continuous flow biocatalysis

J Britton, S Majumdar, GA Weiss - Chemical Society Reviews, 2018 - pubs.rsc.org
The continuous flow synthesis of active pharmaceutical ingredients, value-added chemicals,
and materials has grown tremendously over the past ten years. This revolution in chemical …

Whole-cell biocatalysts by design

B Lin, Y Tao - Microbial cell factories, 2017 - Springer
Whole-cell biocatalysts provide unique advantages and have been widely used for the
efficient biosynthesis of value-added fine and bulk chemicals, as well as pharmaceutically …

The limits to biocatalysis: pushing the envelope

RA Sheldon, D Brady - Chemical communications, 2018 - pubs.rsc.org
In the period 1985 to 1995 applications of biocatalysis, driven by the need for more
sustainable manufacture of chemicals and catalytic,(enantio) selective methods for the …

Development of halogenase enzymes for use in synthesis

J Latham, E Brandenburger, SA Shepherd… - Chemical …, 2018 - ACS Publications
Nature has evolved halogenase enzymes to regioselectively halogenate a diverse range of
biosynthetic precursors, with the halogens introduced often having a profound effect on the …

Bio-methanol as a renewable fuel from waste biomass: current trends and future perspective

P Gautam, SN Upadhyay, SK Dubey - Fuel, 2020 - Elsevier
Use of abundantly available virgin and waste biomasses as feed-stock for producing
gaseous (bio-gas) and liquid fuels (bio-methanol, bio-ethanol and bio-butanol) is being …

Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently

A Currin, N Swainston, PJ Day, DB Kell - Chemical Society Reviews, 2015 - pubs.rsc.org
The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

[HTML][HTML] Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications

B Wiltschi, T Cernava, A Dennig, MG Casas… - Biotechnology …, 2020 - Elsevier
Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

Recent developments of cascade reactions involving ω-transaminases

RC Simon, N Richter, E Busto, W Kroutil - ACS catalysis, 2014 - ACS Publications
Enzymatic cascade reactions experience tremendous attention by cutting short conventional
step-by-step synthesis in a highly efficient and elegant fashion. Focusing on ω …

Estimating the success of enzyme bioprospecting through metagenomics: current status and future trends

M Ferrer, M Martínez‐Martínez, R Bargiela… - Microbial …, 2016 - Wiley Online Library
Recent reports have suggested that the establishment of industrially relevant enzyme
collections from environmental genomes has become a routine procedure. Across the …