Next-generation TB vaccines: progress, challenges, and prospects
L Zhuang, Z Ye, L Li, L Yang, W Gong - Vaccines, 2023 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …
infectious disease and a leading cause of mortality worldwide. Currently, the only available …
Key advances in vaccine development for tuberculosis—Success and challenges
Breakthrough findings in the clinical and preclinical development of tuberculosis (TB)
vaccines have galvanized the field and suggest, for the first time since the development of …
vaccines have galvanized the field and suggest, for the first time since the development of …
The promising potential of reverse vaccinology-based next-generation vaccine development over conventional vaccines against antibiotic-resistant bacteria
The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …
VPM1002 as prophylaxis against severe respiratory tract infections including coronavirus disease 2019 in the elderly: a phase 3 randomized, double-blind, placebo …
AM Blossey, S Brückner, M May… - Clinical Infectious …, 2023 - academic.oup.com
Abstract Background Bacille Calmette-Guérin (BCG) vaccination can potentially reduce the
rate of respiratory infections in vulnerable populations. This study evaluates the safety and …
rate of respiratory infections in vulnerable populations. This study evaluates the safety and …
[HTML][HTML] The cost and cost-effectiveness of novel tuberculosis vaccines in low-and middle-income countries: A modeling study
Background Tuberculosis (TB) is preventable and curable but eliminating it has proven
challenging. Safe and effective TB vaccines that can rapidly reduce disease burden are …
challenging. Safe and effective TB vaccines that can rapidly reduce disease burden are …
The potential impact of novel tuberculosis vaccine introduction on economic growth in low-and middle-income countries: A modeling study
Background Most individuals developing tuberculosis (TB) are working age adults living in
low-and middle-income countries (LMICs). The resulting disability and death impact …
low-and middle-income countries (LMICs). The resulting disability and death impact …
Recent advance in the development of tuberculosis vaccines in clinical trials and virus-like particle-based vaccine candidates
F Zhou, D Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Tuberculosis (TB) remains a serious public health threat around the world. An effective
vaccine is urgently required for cost-effective, long-term control of TB. However, the only …
vaccine is urgently required for cost-effective, long-term control of TB. However, the only …
A Structural View at Vaccine Development against M. tuberculosis
M Romano, F Squeglia, E Kramarska, G Barra… - Cells, 2023 - mdpi.com
Tuberculosis (TB) is still the leading global cause of death from an infectious bacterial agent.
Limiting tuberculosis epidemic spread is therefore an urgent global public health priority. As …
Limiting tuberculosis epidemic spread is therefore an urgent global public health priority. As …
Bridging the gaps to overcome major hurdles in the development of next-generation tuberculosis vaccines
H Kim, HG Choi, SJ Shin - Frontiers in Immunology, 2023 - frontiersin.org
Although tuberculosis (TB) remains one of the leading causes of death from an infectious
disease worldwide, the development of vaccines more effective than bacille Calmette …
disease worldwide, the development of vaccines more effective than bacille Calmette …
Recent developments in mycobacteria-based live attenuated vaccine candidates for tuberculosis
Vaccination is an excellent approach to stimulating the host immune response and reducing
human morbidity and mortality against microbial infections, such as tuberculosis (TB) …
human morbidity and mortality against microbial infections, such as tuberculosis (TB) …