Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …

Kidney fibrosis, characterized by excessive deposition of extracellular matrix (ECM) that
leads to tissue scarring, is the final common outcome of a wide variety of chronic kidney …

Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …

ICAM-1 is a cell surface glycoprotein and an adhesion receptor that is best known for
regulating leukocyte recruitment from circulation to sites of inflammation. However, in …

The WNT–β-catenin system is an evolutionary conserved signalling pathway that is of
particular importance for morphogenesis and cell organization during embryogenesis. The …

Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …

Antiadhesion barriers such as films and hydrogels used to wrap repaired tendons are
important for preventing the formation of adhesion tissue after tendon surgery. However …

Fibrosis, defined by the excess deposition of structural and matricellular proteins in the
extracellular space, underlies tissue dysfunction in multiple chronic diseases. Approved …

Fibrosis is defined as an excessive deposition of connective tissue components and can
affect virtually every organ system, including the skin, lungs, liver and kidney. Fibrotic tissue …

Idiopathic calcium oxalate (CaOx) stones often develop attached to Randall's plaque
present on kidney papillary surfaces. Similar to the plaques formed during vascular …