Lipid nanoparticles for drug delivery

L Xu, X Wang, Y Liu, G Yang… - Advanced …, 2022 - Wiley Online Library
Lipid nanoparticles have attracted significant interests in the last two decades, and have
achieved tremendous clinical success since the first clinical approval of Doxil in 1995. At the …

Preparation of solid lipid nanoparticles and nanostructured lipid carriers for drug delivery and the effects of preparation parameters of solvent injection method

VA Duong, TTL Nguyen, HJ Maeng - Molecules, 2020 - mdpi.com
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have emerged as
potential drug delivery systems for various applications that are produced from …

Lipid-based nanoparticles for drug delivery systems

S Samimi, N Maghsoudnia, RB Eftekhari… - … and biology of …, 2019 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have opened new
horizons in the pharmaceutical industry since they play a fundamental role in the field of …

Nanoparticles and targeted drug delivery in cancer therapy

B Bahrami, M Hojjat-Farsangi, H Mohammadi… - Immunology letters, 2017 - Elsevier
Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

Solid lipid nanoparticles as attractive drug vehicles: Composition, properties and therapeutic strategies

M Geszke-Moritz, M Moritz - Materials Science and Engineering: C, 2016 - Elsevier
This work briefly reviews up-to-date developments in solid lipid nanoparticles (SLNs) as
effective nanocolloidal system for drug delivery. It summarizes SLNs in terms of their …

An updated review on EPR-based solid tumor targeting nanocarriers for cancer treatment

M Sharifi, WC Cho, A Ansariesfahani, R Tarharoudi… - Cancers, 2022 - mdpi.com
Simple Summary One of the important efforts in the treatment of cancers is to achieve
targeted drug delivery by nanocarriers to be more effective and reduce adverse effects …

Nanostructured carriers as innovative tools for cancer diagnosis and therapy

C Martinelli, C Pucci, G Ciofani - APL bioengineering, 2019 - pubs.aip.org
Cancer accounts for millions of deaths every year and, due to the increase and aging of the
world population, the number of new diagnosed cases is continuously rising. Although many …

A combinatorial delivery of survivin targeted siRNA using cancer selective nanoparticles for triple negative breast cancer therapy

P Kesharwani, A Sheikh, MAS Abourehab… - Journal of Drug Delivery …, 2023 - Elsevier
Triple-negative breast cancer (TNBC) is one major type of cancer for which there has been
no effective therapy to date. An important reason for it being the lack of expression of …

Preclinical safety of solid lipid nanoparticles and nanostructured lipid carriers: Current evidence from in vitro and in vivo evaluation

S Doktorovova, AB Kovačević, ML Garcia… - European Journal of …, 2016 - Elsevier
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were designed as
exceptionally safe colloidal carriers for the delivery of poorly soluble drugs. SLN/NLC have …

Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers–a systematic review of in vitro data

S Doktorovova, EB Souto, AM Silva - European Journal of Pharmaceutics …, 2014 - Elsevier
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were developed as
alternative to other colloidal carriers. They were designed to overcome lipid nanoemulsions …