Colorectal cancer (CRC) is a heterogeneous disease with a myriad of alterations at the
cellular and molecular levels. Kristen rat sarcoma (KRAS) mutations occur in up to 40% of …

Chemotherapy-induced peripheral neurotoxicity (CIPN) is a major dose-limiting side effect of
many anti-cancer agents, including taxanes, platinums, vinca alkaloids, proteasome …

(1) Background: Oxaliplatin is among the most neurotoxic anticancer drugs. Little data are
available on the long-term prevalence and consequences of chemotherapy-induced …

Bortezomib is a pivotal drug for the management of multiple myeloma. However, bortezomib
is a neurotoxic anticancer drug responsible for chemotherapy-induced peripheral …

The development of 3D printable hydrogels based on the crosslinking between chitosan and
gelatin is proposed. Chitosan and gelatin were both functionalized with methyl furan groups …

Simple Summary Multiple myeloma (MM) is a still uncurable tumor of mainly elderly patients
originating from the terminally differentiated B cells. Introduction to the treatment of MM …

Purpose Chemotherapy-induced peripheral neurotoxicity (CIPN) is a common dose-limiting
toxicity of cancer treatment causing functional impairment and impacting quality of life …

The proteasome inhibitor bortezomib (BTZ) is a first-line antitumor drug, mainly used for
multiple myeloma treatment. However, BTZ shows prominent toxicity in the peripheral …

Neuromuscular ultrasound is rapidly becoming incorporated into clinical practice as a
standard tool in the assessment of peripheral nerve diseases. Ultrasound complements …

Background Patients with advanced/aggressive multiple myeloma have limited treatment
options to achieve rapid disease control. In eligible patients, bortezomib, dexamethasone …