o-Silylaryl Triflates: A Journey of Kobayashi Aryne Precursors
J Shi, L Li, Y Li - Chemical Reviews, 2021 - ACS Publications
Arynes are among the most active organic intermediates and have found numerous
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …
Progress in the Chemistry of Tetrahydroquinolines
I Muthukrishnan, V Sridharan, JC Menendez - Chemical reviews, 2019 - ACS Publications
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …
widespread in nature and present in a broad variety of pharmacologically active …
Update on melatonin receptors: IUPHAR Review 20
R Jockers, P Delagrange… - British journal of …, 2016 - Wiley Online Library
Melatonin receptors are seven transmembrane‐spanning proteins belonging to the GPCR
superfamily. In mammals, two melatonin receptor subtypes exist‐MT1 and MT2‐encoded by …
superfamily. In mammals, two melatonin receptor subtypes exist‐MT1 and MT2‐encoded by …
Melatonin receptors: molecular pharmacology and signalling in the context of system bias
E Cecon, A Oishi, R Jockers - British journal of pharmacology, 2018 - Wiley Online Library
Melatonin, N‐acetyl‐5‐methoxytryptamine, an evolutionally old molecule, is produced by the
pineal gland in vertebrates, and it binds with high affinity to melatonin receptors, which are …
pineal gland in vertebrates, and it binds with high affinity to melatonin receptors, which are …
XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity
The human MT1 and MT2 melatonin receptors, are G-protein-coupled receptors (GPCRs)
that help to regulate circadian rhythm and sleep patterns. Drug development efforts have …
that help to regulate circadian rhythm and sleep patterns. Drug development efforts have …
Divergent synthesis of nitrogen heterocycles via H 2 O-mediated hydride transfer reactions
F Hu, Z Sun, M Pan, L Wang, L Xu, XL Liu, SS Li - Green Chemistry, 2023 - pubs.rsc.org
The H2O-promoted controllable synthesis of diverse nitrogen heterocycles from readily
available feedstocks was developed by a hydride transfer strategy. A variety of 3-carboxyl …
available feedstocks was developed by a hydride transfer strategy. A variety of 3-carboxyl …
MT1 and MT2 melatonin receptors are expressed in nonoverlapping neuronal populations
P Klosen, S Lapmanee, C Schuster… - Journal of pineal …, 2019 - Wiley Online Library
Melatonin (MLT) exerts its physiological effects principally through two high‐affinity
membrane receptors MT1 and MT2. Understanding the exact mechanism of MLT action …
membrane receptors MT1 and MT2. Understanding the exact mechanism of MLT action …
Activation of melatonin receptor 2 but not melatonin receptor 1 mediates melatonin‐conferred cardioprotection against myocardial ischemia/reperfusion injury
D Han, Y Wang, J Chen, J Zhang, P Yu… - Journal of Pineal …, 2019 - Wiley Online Library
Accumulated pieces of evidence have proved the beneficial effects of melatonin on
myocardial ischemia/reperfusion (MI/R) injury, and these effects were largely dependent on …
myocardial ischemia/reperfusion (MI/R) injury, and these effects were largely dependent on …
Nitrogen-Doped Carbon Supported Nanocobalt Catalyst for Hydrogen-Transfer Dearomative Coupling of Quinolinium Salts and Tetrahydroquinolines
S Xu, Z Cai, C Liao, J Shi, T Wen, F Xie, Z Zhu… - Organic …, 2022 - ACS Publications
A nitrogen-doped carbon supported nanocobalt catalyst was developed and successfully
applied for the hydrogen-transfer coupling of quinolinium salts and tetrahydroquinoline …
applied for the hydrogen-transfer coupling of quinolinium salts and tetrahydroquinoline …
Phosphine-catalyzed [5+ 1] annulation of β′-acetoxy allenoates: straightforward access to tetrahydroquinoline derivatives
Y Zhu, Z Xu, YN Wang - Chemical Communications, 2023 - pubs.rsc.org
An unprecedented phosphine-catalyzed [5+ 1] annulation of β′-acetoxy allenoates with 1,
5-dinucleophiles has been developed, which provides novel and facile access to …
5-dinucleophiles has been developed, which provides novel and facile access to …