The family of Poly (A)-binding proteins (PABPs) regulates the stability and translation of
messenger RNAs (mRNAs). Here we reported that the three members of PABPs, including …

MKRN3 mutations represent the most common genetic cause of central precocious puberty
(CPP) but associations between genotype and clinical features have not been extensively …

This paper presents the eleventh update of the human obesity gene map, which
incorporates published results up to the end of October 2004. Evidence from single‐gene …

Microdeletions of a region termed the" imprinting center"(IC) in chromosome 15q11-q13
have been identified in several families with Prader-Willi syndrome (PWS) or Angelman …

Prader-Willi and Angelman syndromes (PWS and AS) typically result from an∼ 4-Mb
deletion of human chromosome 15q11-q13, with clustered breakpoints (BP) at either of two …

RNA-DNA interactions can serve as a signal that triggers de novo DNA methylation in
plants. As yet, this RNA-directed DNA methylation mechanism merely targets transgenes …

Genetic influences on the determination of human fat mass are profound and powerful, a
statement that does not conflict with the obvious influence of environmental factors that drive …

This is the ninth update of the human obesity gene map, incorporating published results
through October 2002 and continuing the previous format. Evidence from single‐gene …

Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are distinct neurobehavioral
disorders that most often arise from a 4-Mb deletion of chromosome 15q11-q13 during …

Context: Loss-of-function mutations in makorin ring finger 3 (MKRN3), an imprinted gene
located on the long arm of chromosome 15, have been recognized recently as a cause of …