When deciding the appropriate treatment strategy for active ulcerative colitis one should
consider the activity, distribution (proctitis, left-sided, extensive 1), and pattern of disease …

Background & Aims The medical management of ulcerative colitis (UC) has improved
through the development of new therapies and novel approaches that optimize existing …

Catechins are natural polyphenolic phytochemicals that exist in food and medicinal plants,
such as tea, legume and rubiaceae. An increasing number of studies have associated the …

Background The comparative efficacy and safety of infliximab and azathioprine therapy
alone or in combination for Crohn's disease are unknown. Methods In this randomized …

The rapid progress of research into inflammatory bowel disease (IBD) has resulted in
increasingly more treatment options. Different options have different advantages and …

The exciting success of NBTXR3 in the clinic has triggered a tumult of activities in the design
and development of hafnium-based nanoparticles. However, due to the concerns of …

OBJECTIVES: Natural history studies provide invaluable data on the disease course. First,
they help define the end points for clinical trials that are designed to test drugs for the end …

BACKGROUND AND AIMS: We sought to assess the evolution of Crohn's disease behavior
in an American population-based cohort. METHODS: Medical records of all Olmsted County …

Background We did a randomised controlled trial to assess the benefit of maintenance
infliximab therapy in patients with active Crohn's disease who respond to a single infusion of …

Background Infliximab, a chimeric monoclonal antibody directed against tumor necrosis
factor α, is an established treatment for Crohn's disease but not ulcerative colitis. Methods …