This ECCO topical review of the European Crohn's and Colitis Organisation [ECCO] focused
on prediction, diagnosis, and management of fibrostenosing Crohn's disease [CD]. The …

Advances in immunology, biotechnology, and phar-maceutical science have resulted in an
unprecedented number of medications with potential application to the treatment of Crohn's …

Background & Aims: The natural history of pediatric Crohn's disease and risk factors
necessitating surgery have not been thoroughly described. Methods: In a geographically …

The advent of biological therapy has revolutionized inflammatory bowel disease (IBD) care.
Nonetheless, not all patients require biological therapy. Selection of patients depends on …

Background Real‐world data quantifying the costs of increasing use of biologics in
inflammatory bowel disease (IBD) are unknown. Aim To determine the outpatient IBD drug …

Although an extensive body of literature confirmed γ-aminobutyric acid (GABA) as mediator
within the enteric nervous system (ENS) controlling gastrointestinal (GI) function, the true …

Background Selective blockade of interactions between leukocytes and vascular
endothelium in the gut is a promising strategy for the treatment of inflammatory bowel …

Background and aims: This observational study assessed the long-term clinical benefit of
infliximab (IFX) in 614 consecutive patients with Crohn's disease (CD) from a single centre …

Background & Aims: Nutritional therapy has been reported to have an almost equivalent
efficacy of corticosteroids in achieving clinical remission in active Crohn's disease (CD) …

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic joint
inflammation which ultimately leads to severe disability and premature mortality. It has a …