Major neuropsychological impairments in schizophrenia patients: clinical implications
MT Jones, PD Harvey - Current psychiatry reports, 2020 - Springer
Abstract Purpose of Review Schizophrenia is a complex severe mental illness with high
morbidity and mortality. It is characterized by positive symptoms, negative symptoms, and …
morbidity and mortality. It is characterized by positive symptoms, negative symptoms, and …
The sexual brain, genes, and cognition: A machine‐predicted brain sex score explains individual differences in cognitive intelligence and genetic influence in young …
Sex impacts the development of the brain and cognition differently across individuals.
However, the literature on brain sex dimorphism in humans is mixed. We aim to investigate …
However, the literature on brain sex dimorphism in humans is mixed. We aim to investigate …
Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
SY Cui, MX Yang, YH Zhang, V Zheng, HT Zhang… - … of Pharmacology and …, 2019 - ASPET
Recent imaging studies of amyloid and tau in cognitively normal elderly subjects imply that
Alzheimer's pathology can be tolerated by the brain to some extent due to compensatory …
Alzheimer's pathology can be tolerated by the brain to some extent due to compensatory …
Neuroticism polygenic risk predicts conversion from mild cognitive impairment to Alzheimer's disease by impairing inferior parietal surface area
Q Li, X Lv, Q Qian, K Liao, X Du… - Human Brain …, 2024 - Wiley Online Library
The high prevalence of conversion from amnestic mild cognitive impairment (aMCI) to
Alzheimer's disease (AD) makes early prevention of AD extremely critical. Neuroticism, a …
Alzheimer's disease (AD) makes early prevention of AD extremely critical. Neuroticism, a …
[HTML][HTML] Olfactory neuronal cells as a promising tool to realize the “druggable genome” approach for drug discovery in neuropsychiatric disorders
“Druggable genome” is a novel concept that emphasizes the importance of using the
information of genome-wide genetic studies for drug discovery and development. Successful …
information of genome-wide genetic studies for drug discovery and development. Successful …
Genetic overlap profiles of cognitive ability in psychotic and affective illnesses: A multisite study of multiplex pedigrees
EEM Knowles, JM Peralta, L Almasy, V Nimgaonkar… - Biological …, 2021 - Elsevier
Background Cognitive impairment is a key feature of psychiatric illness, making cognition an
important tool for exploring of the genetics of illness risk. It remains unclear which measures …
important tool for exploring of the genetics of illness risk. It remains unclear which measures …
The influence of early moderate prenatal alcohol exposure and maternal diet on offspring DNA methylation: a cross-species study
M Bestry, AN Larcombe, N Kresoje, EK Chivers… - bioRxiv, 2023 - biorxiv.org
Prenatal alcohol exposure (PAE) is associated with changes to offspring DNA methylation
and adverse neurodevelopmental outcomes. Prior studies have utilised candidate gene or …
and adverse neurodevelopmental outcomes. Prior studies have utilised candidate gene or …
Gene, the Sexual Brain, and Cognition: Machine-Predicted Brain Sex Score Explains Individual Differences in Cognitive Development and Genetic Influence.
Sex impacts the development of the brain and cognition differently across individuals. We
investigated the biological underpinnings of the individual variability of sexual dimorphism in …
investigated the biological underpinnings of the individual variability of sexual dimorphism in …