[HTML][HTML] Fibronectin in development and wound healing
Fibronectin structure and composition regulate contextual cell signaling. Recent advances
have been made in understanding fibronectin and its role in tissue organization and repair …
have been made in understanding fibronectin and its role in tissue organization and repair …
Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy
LA Huppert, MD Green, L Kim, C Chow… - Cellular & molecular …, 2022 - nature.com
Decades of advancements in immuno-oncology have enabled the development of current
immunotherapies, which provide long-term treatment responses in certain metastatic cancer …
immunotherapies, which provide long-term treatment responses in certain metastatic cancer …
Regenerative scar-free skin wound healing
Scar formation is a common consequence of skin injuries that lead to a wide range of
adverse effects including physical deformities and psychological disorders. Studies …
adverse effects including physical deformities and psychological disorders. Studies …
Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes
Background Impaired wound healing is the most common and significant complication of
Diabetes. While most other complications of Diabetes have better treatment options, diabetic …
Diabetes. While most other complications of Diabetes have better treatment options, diabetic …
Engineering the IL‐4/IL‐13 axis for targeted immune modulation
ZJ Bernstein, A Shenoy, A Chen… - Immunological …, 2023 - Wiley Online Library
The structurally and functionally related interleukin‐4 (IL‐4) and IL‐13 cytokines play pivotal
roles in shaping immune activity. The IL‐4/IL‐13 axis is best known for its critical role in T …
roles in shaping immune activity. The IL‐4/IL‐13 axis is best known for its critical role in T …
Quercetin improves inflammation, oxidative stress, and impaired wound healing in atopic dermatitis model of human keratinocytes
B Beken, R Serttas, M Yazicioglu… - Pediatric allergy …, 2020 - liebertpub.com
Background: Atopic dermatitis (AD) is a common inflammatory skin disease with complex
pathogenesis. Natural flavonoids exhibit strong anti-inflammatory and antioxidant properties …
pathogenesis. Natural flavonoids exhibit strong anti-inflammatory and antioxidant properties …
Heterogeneity in the initiation, development and function of type 2 immunity
Type 2 immune responses operate under varying conditions in distinct tissue environments
and are crucial for protection against helminth infections and for the maintenance of tissue …
and are crucial for protection against helminth infections and for the maintenance of tissue …
Unraveling the ECM-immune cell crosstalk in skin diseases
The extracellular matrix (ECM) is a complex network of proteins and proteoglycans secreted
by keratinocytes, fibroblasts and immune cells. The function of the skin ECM has expanded …
by keratinocytes, fibroblasts and immune cells. The function of the skin ECM has expanded …
Insights into atopic dermatitis gained from genetically defined mouse models
S Nakajima, T Nomura, J Common… - Journal of Allergy and …, 2019 - Elsevier
Atopic dermatitis (AD) is characterized by severe pruritus and recurrent eczema with a
chronic disease course. Impaired skin barrier function, hyperactivated TH 2 cell–type …
chronic disease course. Impaired skin barrier function, hyperactivated TH 2 cell–type …
Uptake of Staphylococcus aureus by keratinocytes is reduced by interferon–fibronectin pathway and filaggrin expression
R Miyake, K Iwamoto, N Sakai… - The Journal of …, 2022 - Wiley Online Library
Staphylococcus aureus (S. aureus) is frequently detected in the skin of patients with atopic
dermatitis (AD). AD skin‐derived strains of S. aureus (AD strain) are selectively internalized …
dermatitis (AD). AD skin‐derived strains of S. aureus (AD strain) are selectively internalized …