[HTML][HTML] Fibronectin in development and wound healing

J Patten, K Wang - Advanced drug delivery reviews, 2021 - Elsevier
Fibronectin structure and composition regulate contextual cell signaling. Recent advances
have been made in understanding fibronectin and its role in tissue organization and repair …

Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy

LA Huppert, MD Green, L Kim, C Chow… - Cellular & molecular …, 2022 - nature.com
Decades of advancements in immuno-oncology have enabled the development of current
immunotherapies, which provide long-term treatment responses in certain metastatic cancer …

Regenerative scar-free skin wound healing

M Monavarian, S Kader, S Moeinzadeh… - … Engineering Part B …, 2019 - liebertpub.com
Scar formation is a common consequence of skin injuries that lead to a wide range of
adverse effects including physical deformities and psychological disorders. Studies …

Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes

S Nirenjen, J Narayanan, T Tamilanban… - Frontiers in …, 2023 - frontiersin.org
Background Impaired wound healing is the most common and significant complication of
Diabetes. While most other complications of Diabetes have better treatment options, diabetic …

Engineering the IL‐4/IL‐13 axis for targeted immune modulation

ZJ Bernstein, A Shenoy, A Chen… - Immunological …, 2023 - Wiley Online Library
The structurally and functionally related interleukin‐4 (IL‐4) and IL‐13 cytokines play pivotal
roles in shaping immune activity. The IL‐4/IL‐13 axis is best known for its critical role in T …

Quercetin improves inflammation, oxidative stress, and impaired wound healing in atopic dermatitis model of human keratinocytes

B Beken, R Serttas, M Yazicioglu… - Pediatric allergy …, 2020 - liebertpub.com
Background: Atopic dermatitis (AD) is a common inflammatory skin disease with complex
pathogenesis. Natural flavonoids exhibit strong anti-inflammatory and antioxidant properties …

Heterogeneity in the initiation, development and function of type 2 immunity

WC Gause, C Rothlin, P Loke - Nature Reviews Immunology, 2020 - nature.com
Type 2 immune responses operate under varying conditions in distinct tissue environments
and are crucial for protection against helminth infections and for the maintenance of tissue …

Unraveling the ECM-immune cell crosstalk in skin diseases

O Bhattacharjee, U Ayyangar, AS Kurbet… - Frontiers in cell and …, 2019 - frontiersin.org
The extracellular matrix (ECM) is a complex network of proteins and proteoglycans secreted
by keratinocytes, fibroblasts and immune cells. The function of the skin ECM has expanded …

Insights into atopic dermatitis gained from genetically defined mouse models

S Nakajima, T Nomura, J Common… - Journal of Allergy and …, 2019 - Elsevier
Atopic dermatitis (AD) is characterized by severe pruritus and recurrent eczema with a
chronic disease course. Impaired skin barrier function, hyperactivated TH 2 cell–type …

Uptake of Staphylococcus aureus by keratinocytes is reduced by interferon–fibronectin pathway and filaggrin expression

R Miyake, K Iwamoto, N Sakai… - The Journal of …, 2022 - Wiley Online Library
Staphylococcus aureus (S. aureus) is frequently detected in the skin of patients with atopic
dermatitis (AD). AD skin‐derived strains of S. aureus (AD strain) are selectively internalized …