4‐Hydroxycoumarin: A versatile substrate for transition‐metal‐free multicomponent synthesis of bioactive heterocycles

B Borah, K Dhar Dwivedi… - Asian Journal of Organic …, 2021 - Wiley Online Library
One‐pot multi‐component reactions especially under transition‐metal‐free catalysis served
as an efficient, and environmentally friendly method for the construction of value‐added …

Visible light‐induced synthesis of functionalized coumarins

J Singh, A Sharma - Advanced Synthesis & Catalysis, 2021 - Wiley Online Library
Functionalized coumarins are privileged scaffolds which display diverse pharmacological
and physiological activities, and a myriad of applications in medical science and biomedical …

Recent advances in the synthesis and applications of furocoumarin derivatives

C Chen, ZB Tang, Z Liu - Chinese Chemical Letters, 2023 - Elsevier
Furocoumarins are an important class of heterocyclic compounds with a fused tricyclic
structure of coumarin and furan rings. They are commonly found in bioactive natural …

Annulated Heterocyclic[g]Coumarin Composites: Synthetic Approaches and Bioactive Profiling

N Mazin Zeki, Y Fakri Mustafa - Chemistry & Biodiversity, 2024 - Wiley Online Library
Coumarins, widely abundant natural heterocyclic compounds, are extensively employed in
creating various biologically and pharmacologically potent substances. The hybridization of …

Phosphine-Mediated MBH-Type/Acyl Transfer/Wittig Sequence for Construction of Functionalized Furo[3,2-c]coumarins

SS Vagh, BJ Hou, A Edukondalu, PC Wang… - Organic Letters, 2021 - ACS Publications
A new method for the construction of functionalized furo [3, 2-c] coumarins via MBH-type/acyl-
transfer/Wittig reaction is reported. The current approach would open a new route for the …

4-Chloro-3-formylcoumarin as a multifaceted building block for the development of various bio-active substituted and fused coumarin heterocycles: a brief review

P Patra - New Journal of Chemistry, 2021 - pubs.rsc.org
This paper reviews the research data available in the literature on the chemistry of 4-chloro-
3-formylcoumarins reported over the last two to three decades. It covers the synthetic …

A convenient synthesis of furo [3, 2-c] pyran-3-carboxylates from 3-bromo-3-nitroacrylates

VV Pelipko, RI Baichurin, KA Lyssenko… - Mendeleev …, 2022 - Elsevier
Abstract Novel 4-oxo-4H-furo [3, 2-c] pyran-3-carboxylates and 4-oxo-4H-furo [3, 2-c]
chromene-3-carboxylates were prepared from available alkyl 3-bromo-3-nitroacrylates and …

Sc(OTf)3-Mediated One-Pot Synthesis of Coumarin-Fused Furans: A Thiol-Dependent Reaction for the Easy Access of 2-Phenyl-4H-furo[3,2-c]chromen-4-ones

A Jana, D Ali, P Bhaumick… - The Journal of Organic …, 2022 - ACS Publications
Herein, we report a simple and efficient method for the preparation of novel thioether-linked
coumarin-fused furans from the one-pot three-component reaction of arylglyoxal, 4 …

Effective Synthesis and Biological Evaluation of Functionalized 2,3-Dihydrofuro[3,2-c]coumarins via an Imidazole-Catalyzed Green Multicomponent Approach

G Mali, S Maji, KA Chavan, M Shukla, M Kumar… - ACS …, 2022 - ACS Publications
For the first time, an eco-friendly and efficient one-pot green multicomponent approach has
been described to synthesize functionalized trans-2, 3-dihydrofuro [3, 2-c] coumarins …

Copper-Catalyzed Asymmetric Propargylic [3 + 2] Cycloaddition: Synthesis of Enantioenriched Dihydrofuro[3,2-c]coumarins and its Quinolinone and Thiocoumarin …

S Rohilla, S Shah, VK Singh - Organic Letters, 2023 - ACS Publications
A copper (II)-P, N, N-ligand catalyzed propargylic [3+ 2] cycloaddition approach for the
synthesis of optically enriched dihydrofuro [3, 2-c] coumarins has been accomplished for the …