An overview of randomised controlled trials of adjuvant chemotherapy in head and neck cancer

AJ Munro - British journal of cancer, 1995 - nature.com
Meta-analysis of the published results from 54 randomised controlled trials of adjuvant
chemotherapy in head and neck cancer suggests that chemotherapy might increase …

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group

B Lacas, A Carmel, C Landais, SJ Wong… - Radiotherapy and …, 2021 - Elsevier
Abstract Background and purpose The Meta-Analysis of Chemotherapy in squamous cell
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …

Overview of combined modality therapies for head and neck cancer

IW Dimery, WK Hong - JNCI: Journal of the National Cancer …, 1993 - academic.oup.com
The survival rate is 40% for patients with advanced squamous cell carcinoma of the head
and neck whose tumors are completely resected and 20% for those with unresectable …

Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer

E Hartmann, B Wollenberg, S Rothenfusser, M Wagner… - Cancer research, 2003 - AACR
The antitumor activity of IFN-α is well established. However, the role of the plasmacytoid
dendritic cell (PDC), the major producer of IFN-α upon viral infection, in tumor biology is …

Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region. A meta-analysis of prospective and randomized …

S El-Sayed, N Nelson - Journal of clinical oncology, 1996 - ascopubs.org
PURPOSE Using the technique of meta-analysis, we aim to illustrate the potential benefit, or
lack of it, in adding chemotherapy to locoregional definitive treatment in a prospective …

Prognostic factors for survival and tumor control in cervical lymph node metastases from head and neck cancer: a multivariate study of 492 cases

L Cerezo, I Millan, A Torre, G Aragon, J Otero - Cancer, 1992 - Wiley Online Library
A multivariate analysis was carried out in 492 patients with metastatic neck disease from
squamous cell carcinoma to determine the influence of clinical and therapeutic factors on …

A prospective randomized study of chemotherapy adjunctive to definitive radiotherapy in advanced nasopharyngeal carcinoma

ATC Chan, PML Teo, TWT Leung, SF Leung… - International Journal of …, 1995 - Elsevier
Purpose: A prospective randomized trial was conducted to compare chemoradiotherapy
against radiotherapy alone in the treatment of locoregionally advanced nasopharyngeal …

A phase III randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck …

DJ Adelstein, JP Saxton, P Lavertu… - Head & Neck …, 1997 - Wiley Online Library
Background A phase III randomized comparison of radiotherapy alone versus combination
chemotherapy and concurrent continuous‐course radiotherapy was performed at the …

Expanding role of the medical oncologist in the management of head and neck cancer

N Choong, E Vokes - CA: a cancer journal for clinicians, 2008 - Wiley Online Library
The multidisciplinary approach to treating squamous cell carcinoma of the head and neck is
complex and evolving. This article aims to review some recent developments in squamous …

The role of chemotherapy in the management of nasopharyngeal carcinoma

ATC Chan, PML Teo, TWT Leung… - … International Journal of …, 1998 - Wiley Online Library
BACKGROUND Nasopharyngeal carcinoma (NPC) is a radiosensitive tumor for which there
is a high local control rate after radical radiotherapy (RT). However, for patients with …