Fungal species have dynamic genomes and often exhibit genomic plasticity in response to
stress. This genome plasticity often comes with phenotypic consequences that affect fitness …

A century ago experiments with the flowering plant Datura stramonium and the fruit fly
Drosophila melanogaster revealed that adding an extra chromosome to a karyotype was …

Genomic alterations including single-base mutations, deletions and duplications,
translocations, mitotic recombination events, and chromosome aneuploidy generate genetic …

Copy number variants (CNVs), duplications and deletions of genomic sequences, contribute
to evolutionary adaptation but can also confer deleterious effects and cause disease …

Candida albicans is a prevalent human fungal pathogen. Rapid genomic change, due to
aneuploidy, is a common mechanism that facilitates survival from multiple types of stresses …

Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene
functions and allows the generalizability of laboratory findings to be assessed. One notable …

Variation in gene copy number can alter gene expression and influence downstream
phenotypes; thus copy-number variation provides a route for rapid evolution if the benefits …

Forcing budding yeast to chromatinize their DNA with human histones manifests an abrupt
fitness cost. We previously proposed chromosomal aneuploidy and missense mutations as …

Both an increased frequency of chromosome missegregation (chromosomal instability, CIN)
and the presence of an abnormal complement of chromosomes (aneuploidy) are hallmarks …

Diversity within the fungal kingdom is evident from the wide range of morphologies fungi
display as well as the various ecological roles and industrial purposes they serve …