Tumour progression is modulated by the local microenvironment. This environment is
populated by many immune cells, of which macrophages are among the most abundant …

Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

Tumor-associated macrophages (TAMs) as immune cells within the tumor microenvironment
have gained much interests as basic science regarding their roles in tumor progression …

The tumor microenvironment (TME) is an intricate system within solid neoplasms. In this
review, we aim to provide an updated insight into the TME with a focus on the effects of …

Tumor associated macrophages (TAM) enhance the aggressiveness of breast cancer via
promoting cancer cell growth, metastasis, and suppression of the patient's immune system …

Tumour growth and dissemination is largely dependent on nutrient availability. It has
recently emerged that the tumour microenvironment is rich in a diverse array of lipids that …

Simple Summary Macrophages are a major component of the pancreatic tumor
microenvironment, and their increased abundance is associated with poor patient survival …

Pancreatic cancer has a notoriously poor prognosis, exhibits persistent drug resistance, and
lacks a cure. Unique features of the pancreatic tumor microenvironment exacerbate …

A dense desmoplastic stroma formed by abundant extracellular matrix and stromal cells,
including cancer-associated fibroblasts (CAFs) and immune cells, is a feature of pancreatic …

Simple Summary Despite access to a vast arsenal of anticancer agents, many fail to realise
their full therapeutic potential in clinical practice. One key determinant of this is the evolution …