A timeline of tumour-associated macrophage biology
L Cassetta, JW Pollard - Nature Reviews Cancer, 2023 - nature.com
Tumour progression is modulated by the local microenvironment. This environment is
populated by many immune cells, of which macrophages are among the most abundant …
populated by many immune cells, of which macrophages are among the most abundant …
M1/M2 macrophages and their overlaps–myth or reality?
Z Strizova, I Benesova, R Bartolini… - Clinical …, 2023 - portlandpress.com
Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …
Evaluating the polarization of tumor-associated macrophages into M1 and M2 phenotypes in human cancer tissue: technicalities and challenges in routine clinical …
SD Jayasingam, M Citartan, TH Thang… - Frontiers in …, 2020 - frontiersin.org
Tumor-associated macrophages (TAMs) as immune cells within the tumor microenvironment
have gained much interests as basic science regarding their roles in tumor progression …
have gained much interests as basic science regarding their roles in tumor progression …
The role of tumor necrosis factor in manipulating the immunological response of tumor microenvironment
The tumor microenvironment (TME) is an intricate system within solid neoplasms. In this
review, we aim to provide an updated insight into the TME with a focus on the effects of …
review, we aim to provide an updated insight into the TME with a focus on the effects of …
Scavenging reactive oxygen species selectively inhibits M2 macrophage polarization and their pro-tumorigenic function in part, via Stat3 suppression
B Griess, S Mir, K Datta, M Teoh-Fitzgerald - Free Radical Biology and …, 2020 - Elsevier
Tumor associated macrophages (TAM) enhance the aggressiveness of breast cancer via
promoting cancer cell growth, metastasis, and suppression of the patient's immune system …
promoting cancer cell growth, metastasis, and suppression of the patient's immune system …
Diet, lipids, and antitumor immunity
H Prendeville, L Lynch - Cellular & Molecular Immunology, 2022 - nature.com
Tumour growth and dissemination is largely dependent on nutrient availability. It has
recently emerged that the tumour microenvironment is rich in a diverse array of lipids that …
recently emerged that the tumour microenvironment is rich in a diverse array of lipids that …
Tumor-associated macrophages in pancreatic ductal adenocarcinoma: therapeutic opportunities and clinical challenges
AR Poh, M Ernst - Cancers, 2021 - mdpi.com
Simple Summary Macrophages are a major component of the pancreatic tumor
microenvironment, and their increased abundance is associated with poor patient survival …
microenvironment, and their increased abundance is associated with poor patient survival …
Role of the tumor microenvironment in regulating pancreatic cancer therapy resistance
Pancreatic cancer has a notoriously poor prognosis, exhibits persistent drug resistance, and
lacks a cure. Unique features of the pancreatic tumor microenvironment exacerbate …
lacks a cure. Unique features of the pancreatic tumor microenvironment exacerbate …
Opportunities and delusions regarding drug delivery targeting pancreatic cancer-associated fibroblasts
A dense desmoplastic stroma formed by abundant extracellular matrix and stromal cells,
including cancer-associated fibroblasts (CAFs) and immune cells, is a feature of pancreatic …
including cancer-associated fibroblasts (CAFs) and immune cells, is a feature of pancreatic …
Nanomedicine in pancreatic cancer: current status and future opportunities for overcoming therapy resistance
MK Greene, MC Johnston, CJ Scott - Cancers, 2021 - mdpi.com
Simple Summary Despite access to a vast arsenal of anticancer agents, many fail to realise
their full therapeutic potential in clinical practice. One key determinant of this is the evolution …
their full therapeutic potential in clinical practice. One key determinant of this is the evolution …