Earthworm metabolism is recognized as a useful tool for monitoring environmental insults
and measuring ecotoxicity, yet extensive earthworm metabolic profiling using 1H nuclear …

Fourteen polyamine analogues, asymmetric or symmetric substituted spermine (1–9) or
methoctramine (10–14) analogues, were evaluated as potential inhibitors or substrates of …

Protein–nanoparticle hybridization can ideally lead to novel biological entities characterized
by emerging properties that can sensibly differ from those of the parent components. Herein …

Spermine oxidase is a FAD-dependent enzyme that specifically oxidizes spermine, and
plays a central role in the highly regulated catabolism of polyamines in vertebrates. The …

Polyamines are small positively charged alkylamines that are essential in a number of
crucial eukaryotic processes, like normal cell growth and development. In normal …

This study aimed to investigate the effects of spermine and extended spermine
administration on the antioxidant status and expression of NF‐E2‐related factor 2 (Nrf2) …

Neuroblastoma (NB) is a heterogeneous extra‑cranial childhood type of cancer, responsible
for approximately 15% of all paediatric cancer‑related deaths. Although several critical …

N 1-Acetylspermine oxidase (APAO) catalyzes the conversion of N 1-acetylspermine or N 1-
acetylspermidine to spermidine or putrescine, respectively, with concomitant formation of N …

摘要由灰霉菌侵染导致的农作物灰霉病是农业重大病害之一, 采用环境友好型杀菌剂防治灰霉病
受到越来越多的关注. 天然化合物麝香草酚对灰霉菌具有较强的抑菌活性 …

Destruction of cells by irradiation-induced radical formation is one of the most frequent
interventions in cancer therapy. An alternative to irradiation-induced radical formation is in …