Reduced placental CD24 in preterm preeclampsia is an indicator for a failure of immune tolerance

M Sammar, M Siwetz, H Meiri, A Sharabi-Nov… - International Journal of …, 2021 - mdpi.com
Introduction: CD24 is a mucin-like glycoprotein expressed at the surface of hematopoietic
and tumor cells and was recently shown to be expressed in the first trimester placenta. As it …

Identification of structural variation in chimpanzees using optical mapping and nanopore sequencing

DC Soto, C Shew, M Mastoras, JM Schmidt… - Genes, 2020 - mdpi.com
Recent efforts to comprehensively characterize great ape genetic diversity using short-read
sequencing and single-nucleotide variants have led to important discoveries related to …

Placenta-bound and body fluid PP13 and its mRNA in normal pregnancy compared to preeclampsia, HELLP and preterm delivery

M Sammar, S Nisemblat, Z Fleischfarb, A Golan… - Placenta, 2011 - Elsevier
OBJECTIVES: To compare the distribution of placental protein 13 (PP13) in fetal and
maternal blood and amnionic fluid and to correlate it with PP13 protein and mRNA in the …

Galectin-1 and galectin-9 concentration in maternal serum: implications in pregnancies complicated with preterm prelabor rupture of membranes

DG Boroń, A Świetlicki, M Potograbski… - Journal of Clinical …, 2022 - mdpi.com
Preterm prelabor rupture of membranes (pPROM) accounts for nearly half of premature
births. Although several risk factors have been identified, no markers allowing for effective …

The interaction of host and nematode galectins influences the outcome of gastrointestinal nematode infections

K Donskow-Łysoniewska, M Maruszewska-Cheruiyot… - Parasitology, 2021 - cambridge.org
Galectins are a family of proteins that bind β-galactosides and play key roles in a variety of
cellular processes including host defence. They have been well studied in hosts but less so …

Anti-Galectin-2 antibody treatment reduces atherosclerotic plaque size and alters macrophage polarity

J Kane, M Jansen, S Hendrix… - Thrombosis and …, 2022 - thieme-connect.com
Background Galectins have numerous cellular functions in immunity and inflammation. Short-
term galectin-2 (Gal-2) blockade in ischemia-induced arteriogenesis shifts macrophages to …

Placental protein 13 (PP13)-induced vasodilation of resistance arteries from pregnant and nonpregnant rats occurs via endothelial-signaling pathways

T Drobnjak, S Gizurarson, NI Gokina… - Hypertension in …, 2017 - Taylor & Francis
ABSTRACT Placental protein 13 (PP13) induces hypotension in rats. This study aims to
evaluate PP13 effects on isolated uterine arteries from nonpregnant and mid-pregnant rats …

Altered biomarkers in trophoblast cells obtained noninvasively prior to clinical manifestation of perinatal disease

JM Bolnick, HR Kohan-Ghadr, R Fritz, AD Bolnick… - Scientific reports, 2016 - nature.com
A contributing factor to poor placental perfusion, leading to intrauterine growth restriction
and preeclampsia, is the failure of invading extravillous trophoblast (EVT) cells to remodel …

Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB)

SM Blois, S Verlohren, G Wu, G Clark, A Dell… - Seminars in …, 2020 - Springer
Growing evidence suggests that galectins, an evolutionarily conserved family of glycan-
binding proteins, fulfill key roles in pregnancy including blastocyst implantation, maternal …

Galectin signature in normal pregnancy and preeclampsia

SM Blois, G Barrientos - Journal of reproductive immunology, 2014 - Elsevier
Members of the galectin family are expressed within the female reproductive tract and have
been shown to be involved in multiple biological functions that support the progression of …