The aim of the present review is to summarize and evaluate the different mechanisms and
catabolic mediators involved in cancer cachexia and ageing sarcopenia since they may …

The potential for inhibitors of nuclear factor-κB (NF-κB) activation to act as inhibitors of
muscle protein degradation in cancer cachexia has been evaluated both in vitro and in vivo …

Cancer-induced cachexia remains a significant cause of morbidity and mortality in cancer
treatment. Cancer research and development continues at an aggressive pace and yet a …

Chemoprevention, which is referred to as the use of nontoxic natural or synthetic chemicals
to intervene in multistage carcinogenesis, has emerged as a promising and pragmatic …

The cachectic syndrome, characterized by a marked weight loss, anorexia, asthenia and
anemia, is invariably associated with the presence and growth of the tumour and leads to a …

New Findings What is the central question of this study? We sought to examine whether
curcumin could ameliorate skeletal muscle atrophy in diabetic mice by inhibiting protein …

姜黄素是从姜黄中提取的活性成分, 具有广泛的药理作用. 姜黄素利用酚羟基捕捉自由基,
对辐射药物性肝损伤, 氧化损伤起保护作用; 通过调节细胞周期, 诱导细胞凋亡 …

Genetic and epigenetic events have been implicated in the downregulation of the cellular
antigen processing and presentation machinery (APM), which in turn, has been associated …

Muscle cachexia is one of the most critical unmet medical needs. Identifying the molecular
background of cancer-induced muscle loss revealed a promising possibility of new …

Cancer cachexia (CC) is a debilitating multifactorial syndrome, involving progressive
deterioration and functional impairment of skeletal muscles. It affects about 80% of patients …