Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis

C Sandroni, T Cronberg, M Sekhon - Intensive care medicine, 2021 - Springer
Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent
reperfusion of the brain following resuscitation. In those who are admitted to intensive care …

Brain injury biomarkers for predicting outcome after cardiac arrest

J Humaloja, NJ Ashton, MB Skrifvars - Critical Care, 2022 - Springer
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2022. Other selected articles can be found online at https://www …

Performance of a guideline-recommended algorithm for prognostication of poor neurological outcome after cardiac arrest

M Moseby-Knappe, E Westhall, S Backman… - Intensive care …, 2020 - Springer
Purpose To assess the performance of a 4-step algorithm for neurological prognostication
after cardiac arrest recommended by the European Resuscitation Council (ERC) and the …

Hypoxic-ischemic encephalopathy evaluated by brain autopsy and neuroprognostication after cardiac arrest

C Endisch, E Westhall, M Kenda, KJ Streitberger… - JAMA …, 2020 - jamanetwork.com
Importance Neuroprognostication studies are potentially susceptible to a self-fulfilling
prophecy as investigated prognostic parameters may affect withdrawal of life-sustaining …

[HTML][HTML] Brain injury markers in blood predict signs of hypoxic ischaemic encephalopathy on head computed tomography after cardiac arrest

A Lagebrant, M Lang, N Nielsen, K Blennow… - Resuscitation, 2023 - Elsevier
Abstract Background/Aim Signs of hypoxic ischaemic encephalopathy (HIE) on head
computed tomography (CT) predicts poor neurological outcome after cardiac arrest. We …

[HTML][HTML] GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE trial

J Humaloja, M Lähde, NJ Ashton, M Reinikainen… - Resuscitation, 2022 - Elsevier
Aim To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to
predict neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods We …

Automated assessment of brain CT after cardiac arrest—an observational derivation/validation cohort study

M Kenda, M Scheel, A Kemmling, N Aalberts… - Critical Care …, 2021 - journals.lww.com
OBJECTIVES: Prognostication of outcome is an essential step in defining therapeutic goals
after cardiac arrest. Gray-white-matter ratio obtained from brain CT can predict poor …

Duration and clinical features of cardiac arrest predict early severe cerebral edema

CJ Esdaille, PJ Coppler, JW Faro, ZM Weisner… - Resuscitation, 2020 - Elsevier
Background Severe brain edema appears early after cardiopulmonary resuscitation (CPR)
in a subset of patients and portends a poor prognosis. We tested whether clinical features of …

Deep learning-enabled detection of hypoxic–ischemic encephalopathy after cardiac arrest in CT scans: a comparative study of 2D and 3D approaches

NS Molinski, M Kenda, C Leithner, J Nee… - Frontiers in …, 2024 - frontiersin.org
Objective To establish a deep learning model for the detection of hypoxic–ischemic
encephalopathy (HIE) features on CT scans and to compare various networks to determine …

Brain imaging after cardiac arrest

R Beekman, KG Hirsch - Current Opinion in Critical Care, 2023 - journals.lww.com
Brain imaging is important for evaluating the extent of neurologic injury after cardiac arrest.
Future work should focus on addressing previous methodological limitations and …