ABSTRACT IPF is a devastating disease with few therapeutic options. The precise aetiology
of IPF remains elusive. However, our understanding of the pathologic processes involved in …

Idiopathic pulmonary fibrosis (IPF) is a rare and devastating lung disease of unknown
aetiology. Genetic variations in the IL1RN gene, encoding the interleukin-1 receptor …

BACKGROUND: The aim of our study is to investigate correlations of TH1/TH2 cytokine
gene polymorphisms and bronchoalveolar lavage fluid (BALF) cytokine values in interstitial …

Idiopathic interstitial pneumonia (IIP) entails a variable group of lung diseases of unknown
etiology. Idiopathic pulmonary fibrosis, nonspecific interstitial pneumonia, interstitial lung …

An excess of neutrophils in the alveoli and lung interstitium has been described in idiopathic
pulmonary fibrosis (IPF). Engagement of neutrophil Fcγ receptors with IgG complexes may …

Aims We studied the influence of IL-4 gene polymorphisms on the IPF phenotype, ie, extent
of radiological changes (HRCT interstitial (IS) and alveolar (AS) score) and histopathological …

Background A significant genetic component has been described for idiopathic pulmonary
fibrosis (IPF). The R131H (rs1801274) polymorphism of the IgG receptor FcγRIIa determines …

Objective The aim of this study was to analyse whether the polymorphisms of several pro‐
and anti‐inflammatory cytokines may influence the susceptibility to predominantly oral …

AIM: To characterize cytokine gene polymorphisms in patients with idiopathic pulmonary
fibrosis (IPF) compared to healthy controls. METHODS: Fifty-six IPF patients were involved in …

IDIOPATHIC PULMONARY FIBROSIS–CURRENT CONCEPTS IN DIAGNOSIS AND
TREATMENT Idiopathic pulmonary fibrosis (IPF) is a serious disease with a grim prognosis …