Atomically Accurate Design of Metalloproteins with Predefined Coordination Geometries

AM Hoffnagle, FA Tezcan - Journal of the American Chemical …, 2023 - ACS Publications
We report a new computational protein design method for the construction of oligomeric
protein assemblies around metal centers with predefined coordination geometries. We apply …

A Zn-Al-Zr layered double hydroxide/graphene oxide nanocomposite enables rapid photocatalytic removal of kanamycin-resistance bacteria and genes via nano …

M Yu, D Liu, L Wang, J Xia, J Ren, Y Fan, X Zhu… - Applied Catalysis B …, 2024 - Elsevier
For efficient removal of the antibiotic-resistance bacteria and antibiotic-resistance genes,
zirconium-doped zinc-aluminum layered double hydroxide/graphene oxide (Zn-Al-Zr …

Primary and Secondary Coordination Sphere Effects on the Structure and Function of S-Nitrosylating Azurin

C Van Stappen, H Dai, A Jose, S Tian… - Journal of the …, 2023 - ACS Publications
Much progress has been made in understanding the roles of the secondary coordination
sphere (SCS) in tuning redox potentials of metalloproteins. In contrast, the impact of SCS on …

Supramolecular assembling systems of hemoproteins using chemical modifications

K Oohora - Journal of Inclusion Phenomena and Macrocyclic …, 2023 - Springer
Inspired by protein assemblies in biological systems, various artificial protein assemblies
have been constructed in these decades. Hemoprotein containing porphyrin iron complex …

Homologous acetone carboxylases select Fe (II) or Mn (II) as the catalytic cofactor

KA Shisler, WM Kincannon, JR Mattice, J Larson… - Mbio, 2024 - Am Soc Microbiol
Acetone carboxylases (ACs) catalyze the metal-and ATP-dependent conversion of acetone
and bicarbonate to form acetoacetate. Interestingly, two homologous ACs that have been …

Quantifying metal-binding specificity of CcNikZ-II from Clostridium carboxidivorans in the presence of competing metal ions

P Diep, B Kell, A Yakunin, A Hilfinger… - Analytical …, 2023 - Elsevier
Many proteins bind transition metal ions as cofactors to carry out their biological functions.
Despite binding affinities for divalent transition metal ions being predominantly dictated by …

Quantifying metal ion specificity of the nickel-binding protein CcNikZ-II from Clostridium carboxidivorans in the presence of competing metal ions

P Diep, B Kell, A Yakunin, A Hilfinger, R Mahadevan - bioRxiv, 2022 - biorxiv.org
Many proteins bind transition metal ions as cofactors to carry out their biological functions.
Despite binding affinities for divalent transition metal ions being predominantly dictated by …

Metal binding to the Polaris protein associated with ethylene sensing by plants

W MICHAELS - 2023 - etheses.dur.ac.uk
Copper ions are essential to life, but toxic if not tightly regulated. In the model organism
Arabidopsis thaliana, the ER-localised ethylene receptor, ETR1, requires Cu (I) at an …