[HTML][HTML] Mechanisms by which skeletal muscle myokines ameliorate insulin resistance

R Balakrishnan, DC Thurmond - International journal of molecular …, 2022 - mdpi.com
The skeletal muscle is the largest organ in the body and secretes circulating factors,
including myokines, which are involved in various cellular signaling processes. Skeletal …

[HTML][HTML] Autophagy in sarcopenia: Possible mechanisms and novel therapies

G Xie, H Jin, H Mikhail, V Pavel, G Yang, B Ji… - Biomedicine & …, 2023 - Elsevier
With global population aging, age-related diseases, especially sarcopenia, have attracted
much attention in recent years. Characterized by low muscle strength, low muscle quantity or …

[HTML][HTML] Insights into pathogenesis, nutritional and drug approach in sarcopenia: a systematic review

RH Mellen, OS Girotto, EB Marques, LF Laurindo… - Biomedicines, 2023 - mdpi.com
Sarcopenia is a multifactorial condition related to the loss of muscle mass and strength due
to aging, eating habits, physical inactivity, or even caused by another disease. Affected …

[HTML][HTML] The wonder exerkines—novel insights: a critical state-of-the-art review

L Magliulo, D Bondi, N Pini, L Marramiero… - Molecular and cellular …, 2022 - Springer
Several benefits can be acquired through physical exercise. Different classes of
biomolecules are responsible for the cross-talk between distant organs. The secretome of …

[HTML][HTML] Organokines, sarcopenia, and metabolic repercussions: the vicious cycle and the interplay with exercise

G Minniti, LM Pescinini-Salzedas, GAS Minniti… - International journal of …, 2022 - mdpi.com
Sarcopenia is a disease that becomes more prevalent as the population ages, since it is
directly linked to the process of senility, which courses with muscle atrophy and loss of …

Atrophic skeletal muscle fibre‐derived small extracellular vesicle miR‐690 inhibits satellite cell differentiation during ageing

X Shao, W Gong, Q Wang, P Wang… - Journal of Cachexia …, 2022 - Wiley Online Library
Background Sarcopenia is a common and progressive skeletal muscle disorder
characterized by atrophic muscle fibres and contractile dysfunction. Accumulating evidence …

[HTML][HTML] Non-alcoholic steatohepatitis (NASH) and organokines: What is now and what will be in the future

JPM Santos, MC Maio, MA Lemes, LF Laurindo… - International Journal of …, 2022 - mdpi.com
Non-alcoholic steatohepatitis (NASH) is characterized by steatosis, lobular inflammation,
and enlargement of the diameter of hepatocytes (ballooning hepatocytes), with or without …

Effects of exercise intensity on white adipose tissue browning and its regulatory signals in mice

R Tanimura, L Kobayashi, T Shirai… - Physiological …, 2022 - Wiley Online Library
Adipose tissue has been classified into white adipose tissue (WAT), brown adipose tissue
(BAT), and beige adipose tissue the latter of which is produced as WAT changes into BAT …

[HTML][HTML] Electrical impedance myography detects age-related skeletal muscle atrophy in adult zebrafish

SB Rutkove, S Callegari, H Concepcion, T Mourey… - Scientific Reports, 2023 - nature.com
Age-related deficits in skeletal muscle function, termed sarcopenia, are due to loss of muscle
mass and changes in the intrinsic mechanisms underlying contraction. Sarcopenia is …

[HTML][HTML] Docosahexaenoic acid, a potential treatment for sarcopenia, modulates the ubiquitin–proteasome and the autophagy–lysosome systems

JH Lee, JH Jeon, MJ Lee - Nutrients, 2020 - mdpi.com
One of the characteristic features of aging is the progressive loss of muscle mass, a
nosological syndrome called sarcopenia. It is also a pathologic risk factor for many clinically …