Bidirectional relationships of comorbidity with obstructive sleep apnoea

M Gleeson, WT McNicholas - European respiratory review, 2022 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is frequently associated with comorbidities that include
metabolic, cardiovascular, renal, pulmonary and neuropsychiatric. There is considerable …

Complications of obesity

D Kinlen, D Cody, D O'Shea - QJM: An International Journal of …, 2018 - academic.oup.com
Global obesity rates have increased exponentially in recent decades. People are becoming
obese younger, morbid obesity is increasing and the full health implications are only …

[HTML][HTML] DNA methylation and body-mass index: a genome-wide analysis

KJ Dick, CP Nelson, L Tsaprouni, JK Sandling, D Aïssi… - The Lancet, 2014 - thelancet.com
Background Obesity is a major health problem that is determined by interactions between
lifestyle and environmental and genetic factors. Although associations between several …

[HTML][HTML] Obstructive sleep apnea and comorbidities: a dangerous liaison

MR Bonsignore, P Baiamonte, E Mazzuca… - Multidisciplinary …, 2019 - Springer
Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated
with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged …

Hypoxia and adipose tissue function and dysfunction in obesity

P Trayhurn - Physiological reviews, 2013 - journals.physiology.org
The rise in the incidence of obesity has led to a major interest in the biology of white adipose
tissue. The tissue is a major endocrine and signaling organ, with adipocytes, the …

Diabetes mellitus prevalence and control in sleep-disordered breathing: the European Sleep Apnea Cohort (ESADA) study

BD Kent, L Grote, S Ryan, JL Pepin, MR Bonsignore… - Chest, 2014 - Elsevier
BACKGROUND OSA is associated with an increased risk of cardiovascular morbidity. A
driver of this is metabolic dysfunction and in particular type 2 diabetes mellitus (T2DM). Prior …

Metabolic syndrome and the lung

CW Baffi, L Wood, D Winnica, PJ Strollo Jr, MT Gladwin… - Chest, 2016 - Elsevier
A link between metabolic syndrome (MetS) and lung diseases has been observed in several
cross-sectional and longitudinal studies. This syndrome has been identified as an …

[HTML][HTML] Clinical problems caused by obesity

I Kyrou, HS Randeva, C Tsigos, G Kaltsas… - 2015 - europepmc.org
4. Dr. Gregory Kaltsas MD FRCP (Lon) is a Professor in General Medicine and
Endocrinology at the National and Kapodistrian University of Athens, Greece. He was …

Obesity and obstructive sleep apnea–clinical significance of weight loss

H Tuomilehto, J Seppä, M Uusitupa - Sleep medicine reviews, 2013 - Elsevier
Obesity is a major health burden that contributes to increased morbidity and mortality.
Obesity is also the most important risk factor for obstructive sleep apnea (OSA); at least 70 …

The relationship between obstructive sleep apnea syndrome and obesity: A new perspective on the pathogenesis in terms of organ crosstalk

N Kuvat, H Tanriverdi, F Armutcu - The clinical respiratory …, 2020 - Wiley Online Library
Introduction Obstructive sleep apnea syndrome (OSAS) is a common disorder that has a
major impact on public health. The connection between OSAS and obesity is very complex …