Recent developments of magnetic nanoparticles for theranostics of brain tumor

M Shevtsov, G Multhoff - Current drug metabolism, 2016 - ingentaconnect.com
Background: Glioblastoma multiforme, one of the most aggressive brain tumors, has a very
poor clinical outcome. Despite the introduction of the alkylating reagent temozolomide (TMZ) …

Study on doxorubicin loading on differently functionalized iron oxide nanoparticles: Implications for controlled drug-delivery application

VR Khabibullin, MR Chetyrkina, SI Obydennyy… - International Journal of …, 2023 - mdpi.com
Nanoplatforms applied for the loading of anticancer drugs is a cutting-edge approach for
drug delivery to tumors and reduction of toxic effects on healthy cells. In this study, we …

ScFv-conjugated superparamagnetic iron oxide nanoparticles for MRI-based diagnosis in transgenic mouse models of Parkinson's and Huntington's diseases

X Liu, S Lu, D Liu, L Zhang, L Zhang, X Yu, R Liu - Brain research, 2019 - Elsevier
It is widely accepted that amyloid oligomers are the most toxic species to initiate the
pathologic processes of Parkinson's disease (PD) and Huntingdon's disease (HD). But there …

Real-time liver uptake and biodistribution of magnetic nanoparticles determined by AC biosusceptometry

CC Quini, AG Próspero, MFF Calabresi… - … , Biology and Medicine, 2017 - Elsevier
We describe the development of a joint in vivo/ex vivo protocol to monitor magnetic
nanoparticles in animal models. Alternating current biosusceptometry (ACB) enables the …

Fabrication and cytotoxicity of gemcitabine-functionalized magnetite nanoparticles

RC Popescu, E Andronescu, BȘ Vasile, R Truşcă… - Molecules, 2017 - mdpi.com
Nanotechnology has been successfully used for the fabrication of targeted anti-cancer drug
carriers. This study aimed to obtain Fe3O4 nanoparticles functionalized with Gemcitabine to …

Magnetic nanoparticles conjugated with peptides derived from monocyte chemoattractant protein-1 as a tool for targeting atherosclerosis

CW Kao, PT Wu, MY Liao, IJ Chung, KC Yang… - Pharmaceutics, 2018 - mdpi.com
Atherosclerosis is a multifactorial inflammatory disease that may progress silently for long
period, and it is also widely accepted as the main cause of cardiovascular diseases. To …

Fabrication of anisotropic Cu ferrite-polymer core-shell nanoparticles for photodynamic ablation of cervical cancer cells

SH Kuo, PT Wu, JY Huang, CP Chiu, J Yu, MY Liao - Nanomaterials, 2020 - mdpi.com
In this work we developed methylene blue-immobilized copper-iron nanoparticles (MB-CuFe
NPs) through a facile one-step hydrothermal reaction to achieve a better phototherapeutic …

Interaction between Pharmaceutical Drugs and Polymer-Coated Fe3O4 Magnetic Nanoparticles with Langmuir Monolayers as Cellular Membrane Models

SN Moya Betancourt, CI Cámara, JS Riva - Pharmaceutics, 2023 - mdpi.com
Surface modification of magnetic nanoparticles (MNPs) has been reported to play a
significant role in determining their interactions with cell membranes. In this research, the …

A new pharmacokinetic model describing the biodistribution of intravenously and intratumorally administered superparamagnetic iron oxide nanoparticles (SPIONs) in …

AP Klapproth, M Shevtsov, S Stangl, WB Li… - International Journal …, 2020 - Taylor & Francis
Background Superparamagnetic iron oxide nanoparticles (SPIONs) have displayed
multifunctional applications in cancer theranostics following systemic delivery. In an effort to …

Targeted and theranostic applications for nanotechnologies in medicine

S Setua, M Jaggi, MM Yallapu, SC Chauhan… - … in Preventive and …, 2018 - Elsevier
Abstract The International Agency for Research on Cancer of the World Health Organization
predicts that there will be∼ 13–17 million cancer-related deaths each year worldwide by …