[HTML][HTML] Obesity and COVID-19: molecular mechanisms linking both pandemics

A Ritter, NN Kreis, F Louwen, J Yuan - International journal of molecular …, 2020 - mdpi.com
The coronavirus disease 2019 COVID-19 pandemic is rapidly spreading worldwide and is
becoming a major public health crisis. Increasing evidence demonstrates a strong …

An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease

F Maltais, M Decramer, R Casaburi… - American journal of …, 2014 - atsjournals.org
Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance …

[HTML][HTML] A systematic review and meta-analysis of obesity and COVID-19 outcomes

X Zhang, AM Lewis, JR Moley, JR Brestoff - Scientific reports, 2021 - nature.com
Some studies report that obesity is associated with more severe symptoms following SARS-
CoV-2 infection and worse COVID-19 outcomes, however many other studies have not …

[HTML][HTML] Obesity, the most common comorbidity in SARS-CoV-2: is leptin the link?

CJ Rebello, JP Kirwan, FL Greenway - International Journal of Obesity, 2020 - nature.com
Overweight and obesity are major risk factors for diabetes, cardiovascular disease, and lung
disease. These diseases are the most commonly reported health conditions that predispose …

[HTML][HTML] Effect of long-term exposure to fine particulate matter on lung function decline and risk of chronic obstructive pulmonary disease in Taiwan: a longitudinal …

C Guo, Z Zhang, AKH Lau, CQ Lin… - The Lancet Planetary …, 2018 - thelancet.com
Background Information on the effects of long-term exposure to fine particulate matter with
an aerodynamic diameter of 2· 5 μm or less (PM 2· 5) on lung health is scarce. We aimed to …

Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis

M Adam, T Schikowski, AE Carsin, Y Cai… - European respiratory …, 2015 - Eur Respiratory Soc
The chronic impact of ambient air pollutants on lung function in adults is not fully understood.
The objective of this study was to investigate the association of long-term exposure to …

Obesity and SARS‐CoV‐2: a population to safeguard

M Watanabe, R Risi, D Tuccinardi… - Diabetes/Metabolism …, 2020 - Wiley Online Library
Evidence has lately emerged regarding an increased risk of SARS‐CoV‐2 with worse
prognosis in patients with obesity, especially among the young. Weight excess is a well …

The impact of obesity on the immune response to infection

JJ Milner, MA Beck - Proceedings of the Nutrition Society, 2012 - cambridge.org
There is strong evidence indicating that excess adiposity negatively impacts immune
function and host defence in obese individuals. This is a review of research findings …

Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF

DF Quail, OC Olson, P Bhardwaj, LA Walsh… - Nature cell …, 2017 - nature.com
Obesity is associated with chronic, low-grade inflammation, which can disrupt homeostasis
within tissue microenvironments. Given the correlation between obesity and relative risk of …

[HTML][HTML] Hypercoagulopathy and adipose tissue exacerbated inflammation may explain higher mortality in COVID-19 patients with obesity

G Pasquarelli-do-Nascimento… - Frontiers in …, 2020 - frontiersin.org
COVID-19, caused by SARS-CoV-2, is characterized by pneumonia, lymphopenia,
exhausted lymphocytes and a cytokine storm. Several reports from around the world have …