Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …

Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …

Exosomes participate in cancer progression and metastasis by transferring bioactive
molecules between cancer and various cells in the local and distant microenvironments …

It is clear that exosomes (endosome derived vesicles) serve important roles in cellular
communication both locally and distally and that the exosomal process is abnormal in …

Chronic myeloid leukemia (CML) has been a “model disease” with a long history. Beginning
with the first discovery of leukemia and the description of the Philadelphia Chromosome and …

Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …

Background CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC),
displaying aggressive and metastatic phenotype. Using two different in vitro models, already …

Human umbilical cord mesenchymal stem cells (hucMSCs) and their exosomes have been
considered as potential therapeutic tools for tissue regeneration; however, the underlying …

Cell to cell communication is essential for the coordination and proper organization of
different cell types in multicellular systems. Cells exchange information through a multitude …