Proliferation and activation of microglia in the brain, concentrated around amyloid plaques,
is a prominent feature of Alzheimer's disease (AD). Human genetics data point to a key role …

Background: The Religious Orders Study and Rush Memory and Aging Project are both
ongoing longitudinal clinical-pathologic cohort studies of aging and Alzheimer's disease …

Worldwide, there are nearly 10 million new cases of dementia annually, of which
Alzheimer's disease (AD) is the most common. New measures are needed to improve the …

This article describes the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on …

Neurodegenerative disorders are characterized by the progressive dysfunction and death of
selectively vulnerable neuronal populations, often associated with the accumulation of …

Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …

This report describes the public health impact of Alzheimer's disease, including incidence
and prevalence, mortality rates, costs of care, and the overall impact on caregivers and …

Background—Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative
disease that is characterized by memory loss, personality changes, and a decline in …

Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …

This article describes the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality rates, costs of care, and the overall impact on caregivers …