Toxoplasma gondii‐induced neuronal alterations
A Parlog, D Schlüter, IR Dunay - Parasite immunology, 2015 - Wiley Online Library
The zoonotic pathogen Toxoplasma gondii infects over 30% of the human population. The
intracellular parasite can persist lifelong in the CNS within neurons modifying their function …
intracellular parasite can persist lifelong in the CNS within neurons modifying their function …
[HTML][HTML] Neurogliaform and ivy cells: a major family of nNOS expressing GABAergic neurons
C Armstrong, E Krook-Magnuson… - Frontiers in neural circuits, 2012 - frontiersin.org
Neurogliaform and Ivy cells are members of an abundant family of neuronal nitric oxide
synthase (nNOS) expressing GABAergic interneurons found in diverse brain regions. These …
synthase (nNOS) expressing GABAergic interneurons found in diverse brain regions. These …
Resveratrol mitigates the oxidative stress mediated by hypoxic-ischemic brain injury in neonatal rats via Nrf2/HO-1 pathway
Y Gao, R Fu, J Wang, X Yang, L Wen… - Pharmaceutical …, 2018 - Taylor & Francis
Context: Hypoxic-ischemic encephalopathy (HIE) has a high morbidity and mortality rate.
Resveratrol possesses numerous biological properties including antioxidant, anti …
Resveratrol possesses numerous biological properties including antioxidant, anti …
G-CSF attenuates neuroinflammation and stabilizes the blood–brain barrier via the PI3K/Akt/GSK-3β signaling pathway following neonatal hypoxia-ischemia in rats
Objective Neonatal hypoxia occurs in approximately 60% of premature births and is
associated with a multitude of neurological disorders. While various treatments have been …
associated with a multitude of neurological disorders. While various treatments have been …
HIV-1 Tat causes cognitive deficits and selective loss of parvalbumin, somatostatin, and neuronal nitric oxide synthase expressing hippocampal CA1 interneuron …
Memory deficits are characteristic of HIV-associated neurocognitive disorders (HAND) and
co-occur with hippocampal pathology. The HIV-1 transactivator of transcription (Tat), a …
co-occur with hippocampal pathology. The HIV-1 transactivator of transcription (Tat), a …
Synaptic dysregulation and hyperexcitability induced by intracellular amyloid beta oligomers
EJ Fernandez‐Perez, B Muñoz, DA Bascuñan… - Aging cell, 2021 - Wiley Online Library
Intracellular amyloid beta oligomer (iAβo) accumulation and neuronal hyperexcitability are
two crucial events at early stages of Alzheimer's disease (AD). However, to date, no …
two crucial events at early stages of Alzheimer's disease (AD). However, to date, no …
Neuronal nitric oxide synthase-dependent S-nitrosylation of gephyrin regulates gephyrin clustering at GABAergic synapses
B Dejanovic, G Schwarz - Journal of Neuroscience, 2014 - Soc Neuroscience
Gephyrin, the principal scaffolding protein at inhibitory synapses, is essential for
postsynaptic clustering of glycine and GABA type A receptors (GABAARs). Gephyrin cluster …
postsynaptic clustering of glycine and GABA type A receptors (GABAARs). Gephyrin cluster …
G-CSF ameliorates neuronal apoptosis through GSK-3β inhibition in neonatal hypoxia–ischemia in rats
Granulocyte-colony stimulating factor (G-CSF), a growth factor, has known neuroprotective
effects in a variety of experimental brain injury models. Herein we show that G-CSF …
effects in a variety of experimental brain injury models. Herein we show that G-CSF …
NO-sGC-cGMP signaling influence the anxiolytic like effect of lithium in mice in light and dark box and elevated plus maze
Glutamate is an excitatory neurotransmitter implicated in the pathogenesis of psychiatric
disorders. Glutamate results in the activation of an enzyme called glycogen synthase kinase …
disorders. Glutamate results in the activation of an enzyme called glycogen synthase kinase …
N-Acetylaspartylglutamate (NAAG) Pretreatment Reduces Hypoxic-Ischemic Brain Damage and Oxidative Stress in Neonatal Rats
E Bratek, A Ziembowicz, E Salinska - Antioxidants, 2020 - mdpi.com
N-acetylaspartylglutamate (NAAG), the most abundant peptide transmitter in the mammalian
nervous system, activates mGluR3 at presynaptic sites, inhibiting the release of glutamate …
nervous system, activates mGluR3 at presynaptic sites, inhibiting the release of glutamate …