The ins and outs of the caudal nucleus of the solitary tract: An overview of cellular populations and anatomical connections

MK Holt - Journal of Neuroendocrinology, 2022 - Wiley Online Library
The body and brain are in constant two‐way communication. Driving this communication is a
region in the lower brainstem: the dorsal vagal complex. Within the dorsal vagal complex …

Involvement of the dorsal vagal complex in alcohol-related behaviors

BN Keller, A Hajnal, KN Browning… - Frontiers in Behavioral …, 2022 - frontiersin.org
The neurobiological mechanisms that regulate the development and maintenance of alcohol
use disorder (AUD) are complex and involve a wide variety of within and between systems …

Unilateral vagotomy alters astrocyte and microglial morphology in the nucleus tractus solitarii of the rat

GC Hofmann, EM Hasser… - American Journal of …, 2021 - journals.physiology.org
The nucleus tractus solitarii (nTS) is the initial site of integration of sensory information from
the cardiorespiratory system and contributes to reflex responses to hypoxia. Afferent fibers of …

Glial modulation of energy balance: The dorsal vagal complex is no exception

JD Troadec, S Gaigé, M Barbot, B Lebrun… - International Journal of …, 2022 - mdpi.com
The avoidance of being overweight or obese is a daily challenge for a growing number of
people. The growing proportion of people suffering from a nutritional imbalance in many …

Neonatal Chlamydia muridarum respiratory infection causes neuroinflammation within the brainstem during the early postnatal period

KE Hedley, HM Gomez, E Kecelioglu… - Journal of …, 2024 - Springer
Respiratory infections are one of the most common causes of illness and morbidity in
neonates worldwide. In the acute phase infections are known to cause wide-spread …

The many faces of G protein-coupled receptor 143, an atypical intracellular receptor

B Bueschbell, P Manga, AC Schiedel - Frontiers in Molecular …, 2022 - frontiersin.org
GPCRs transform extracellular stimuli into a physiological response by activating an
intracellular signaling cascade initiated via binding to G proteins. Orphan G protein-coupled …

The relationship between SGLT2 and systemic blood pressure regulation

P Ahwin, D Martinez - Hypertension Research, 2024 - nature.com
The sodium-glucose cotransporter 2 (SGLT2) is a glucose transporter that is located within
the proximal tubule of the kidney's nephrons. While it is typically associated with the kidney …

Vagotomy blunts cardiorespiratory responses to vagal afferent stimulation via pre‐and postsynaptic effects in the nucleus tractus solitarii

GC Hofmann, P Gama de Barcellos Filho… - The Journal of …, 2024 - Wiley Online Library
Viscerosensory information travels to the brain via vagal afferents, where it is first integrated
within the brainstem nucleus tractus solitarii (nTS), a critical contributor to cardiorespiratory …

Interplay between systemic metabolic cues and autonomic output: connecting cardiometabolic function and parasympathetic circuits

L Espinoza, S Fedorchak, CR Boychuk - Frontiers in Physiology, 2021 - frontiersin.org
There is consensus that the heart is innervated by both the parasympathetic and
sympathetic nervous system. However, the role of the parasympathetic nervous system in …

Constitutively active microglial populations limit anorexia induced by the food contaminant deoxynivalenol

S Gaige, R Barbouche, M Barbot, S Boularand… - Journal of …, 2022 - Springer
Microglia are involved in neuroinflammatory processes during diverse pathophysiological
conditions. To date, the possible contribution of these cells to deoxynivalenol (DON) …