Over the last few years there have been a number of reviews on ketogenesis and its control
(see sect. III), but ketone-body utilization, in contrast, has been somewhat neglected. The …

The rate of the tricarboxylic acid cycle is determined by the first step, the citrate synthase
reaction. The rate of this reaction depends on the concentrations of the two substrates …

The mitochondria of various tissues from mice, naked mole rats (NMRs), and bats possess
two mechanistically similar systems to prevent the generation of mitochondrial reactive …

1. The concentrations of the oxidized and reduced substrates of the 'malic'enzyme (EC 1.1.
1.40) and isocitrate dehydrogenase (EC 1.1. 1.42) were measured in freeze-clamped rat …

Streptozotocin, when administered to rats (65 mg. per kg. intravenously), gives rise to
diabetes characterised by a specific hyperglycæmia with virtually no ketosis or elevation of …

A new apparatus is described which removes and freezes brains of conscious rats more
rapidly than was heretofore possible. The apparatus consists of two probes which are driven …

Diabetic cardiomyopathy is a distinct pathology independent of co-morbidities such as
coronary artery disease and hypertension. Diminished glucose uptake due to impaired …

Under conditions used previously for demonstrating glycolytic oscillations in muscle extracts
(pH 6.65, 0.1 to 0.5 mM ATP), phosphofructokinase from rat skeletal muscle is strongly …

The kinetics of changes in the tissue content of citric acid cycle intermediates and free amino
acids have been investigated in isolated perfused hearts during the transition from substrate …

Oxygen uptake in skeletal muscle mitochondria respiring on pyruvate or on acetylcarnitine
plus propionylcarnitine is stimulated 3–4‐fold by bicarbonate. The stimulation is highly …