The synaptic hypothesis of schizophrenia has been highly influential. However, new
approaches mean there has been a step-change in the evidence available, and some tenets …

The recent shift in sociopolitical debates and growing liberalization of cannabis use across
the globe has raised concern regarding its impact on vulnerable populations, such as …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …

Synaptic dysfunction is hypothesised to play a key role in schizophrenia pathogenesis, but
this has not been tested directly in vivo. Here, we investigated synaptic vesicle glycoprotein …

The surgical management of brain tumors is based on the principle that the extent of
resection improves patient outcomes. Traditionally, neurosurgeons have considered that …

Youth depression has been associated with heterogenous patterns of aberrant brain
connectivity. To make sense of these divergent findings, we conducted a systematic review …

Brain network models of cognitive control are central to advancing our understanding of
psychopathology and cognitive dysfunction in schizophrenia. This review examines the role …

Importance Altered functional connectivity (FC) is a common finding in resting-state
functional magnetic resonance imaging (rs-fMRI) studies of people with psychosis, yet how …

In recent years, machine learning (ML) has been a promising approach in the research of
treatment outcome prediction in psychosis. In this study, we reviewed ML studies using …

Cannabis use during the critical neurodevelopmental period of adolescence, may lead to
brain structural, functional, and histological alterations that may underpin some of the longer …