Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …

Mass spectrometry imaging (MSI) is an emerging technology in cancer metabolomics.
Desorption electrospray ionization (DESI) and matrix-assisted laser desorption ionization …

Optical microscopes today have pushed the limits of speed, quality, and observable space in
biological specimens revolutionizing how we view life today. Further, specific labeling of …

Subcellular compartmentalization ensures orderly and efficient intracellular metabolic
activities in eukaryotic life. Investigation of the subcellular metabolome could provide in …

Developing an imaging method with micrometer-to-subcellular resolution is of great
significance for visualizing biological samples of different sizes. The label-free and high …

Oral cancer is the 16th most common cancer worldwide. It commonly arises from painless
white or red plaques within the oral cavity. Clinical outcome is highly related to the stage …

Cancer cells rewire their metabolism to survive during cancer progression. In this context,
tumour metabolic heterogeneity arises and develops in response to diverse environmental …

As cell signaling research has advanced, it has become clearer that signal transduction has
complex spatiotemporal regulation that goes beyond foundational linear transduction …

High-performance metabolic diagnosis-based laser desorption/ionization mass
spectrometry (LDI-MS) improves the precision diagnosis of diseases and subsequent …

Subcellular metabolomics analysis is crucial for understanding intracellular heterogeneity
and accurate drug–cell interactions. Unfortunately, the ultra-small size and complex …