The phenotypic changes of Schwann cells promote the functional repair of nerve injury

S Liao, Y Chen, Y Luo, M Zhang, J Min - Neuropeptides, 2024 - Elsevier
Functional recovery after nerve injury is a significant challenge due to the complex nature of
nerve injury repair and the non-regeneration of neurons. Schwann cells (SCs), play a crucial …

Beneficial Effects of Human Schwann Cell-Derived Exosomes in Mitigating Secondary Damage After Penetrating Ballistic-Like Brain Injury

K Nishimura, J Sanchez-Molano, N Kerr… - Journal of …, 2024 - liebertpub.com
There is a growing body of evidence that the delivery of cell-derived exosomes normally
involved in intracellular communication can reduce secondary injury mechanisms after brain …

Schwann Cell-Derived Exosomes Induced Axon Growth after Spinal Cord Injury by Decreasing PTP-σ Activation on CSPGs via the Rho/ROCK Pathway

S Zhu, H Ma, M Hou, H Li, G Ning - Neurochemical Research, 2024 - Springer
Spinal cord injury (SCI) is a severe neurological condition that involves a lengthy
pathological process. This process leads to the upregulation of chondroitin sulfate …

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

PJ Goldschmidt-Clermont, A Khan… - Neural Regeneration … - journals.lww.com
Schwann cells are essential for the maintenance and function of motor neurons, axonal
networks, and the neuromuscular junction. In amyotrophic lateral sclerosis, where motor …