Mesenchymal stromal cells (MSCs) are a subset of heterogeneous, non-hematopoietic
fibroblast-like cells which play important roles in tissue repair, inflammation, and immune …

Adipocyte is a unique and versatile component of bone marrow microenvironment (BMM).
However, the dynamic evolution of Bone Marrow (BM) adipocytes from the diagnosis of B …

This comprehensive review delves into the multifaceted roles of mesenchymal stem cells
(MSCs) in leukemia, focusing on their interactions within the bone marrow microenvironment …

Immune system and bone marrow stromal cells play an important role in maintaining normal
hematopoiesis. Lymphoid neoplasia disturbs not only development of immune cells, but …

Extensive research over the past 50 years has resulted in significant improvements in
survival for patients diagnosed with leukemia. Despite this, a subgroup of patients harboring …

As our understanding of mesenchymal stromal cells (MSC) has evolved, they have come to
be recognized as an integral part of the tumor tissue, and the exploitability of their intrinsic …

The translocation between chromosomes 4 and 11 generating the KMT2A/AFF1 (will be
referred to as MLL/AF4) fusion gene remains one of the most prevalent cytogenetic subtypes …

Presence of minimal residual disease (MRD), detected by flow cytometry, is an important
prognostic biomarker in the management of B-cell precursor acute lymphoblastic leukemia …