Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest
animals are the single best source of marine natural products. The present review presents …

Covering: through 2014 Many organisms team up with microbes for defense against
predators, parasites, parasitoids, or pathogens. Here we review the described protective …

The largely unexplored marine world that presumably harbors the most biodiversity may be
the vastest resource to discover novel 'validated'structures with novel modes of action that …

Emiliania huxleyi, an environmentally important marine microalga, has a bloom-and-bust
lifestyle in which massive algal blooms appear and fade. Phaeobacter gallaeciensis …

Covering: up to the end of 2008 This review discusses the biosynthesis of natural products
that are generated by trans-AT polyketide synthases, a family of catalytically versatile …

Foreknowledge of the secondary metabolic potential of cultivated and previously
uncultivated microorganisms can potentially facilitate the process of natural product …

Due to their eukaryotic heritage, the differences between a fungal pathogen's molecular
makeup and its human host are small. Therefore, the discovery and subsequent …

Coumarins are a structurally varied set of 2 H-chromen-2-one compounds categorized also
as members of the benzopyrone group of secondary metabolites. Coumarin derivatives …

An important unresolved issue in microbial secondary metabolite production is the
abundance of biosynthetic gene clusters that are not expressed under typical laboratory …

In the marine environment, all hard surfaces including marine macroorganims are colonized
by microorganisms mainly from the surrounding environment. The microorganisms …