Polymer incorporated magnetic nanoparticles: Applications for magnetoresponsive targeted drug delivery

F Sharifianjazi, M Irani, A Esmaeilkhanian… - Materials Science and …, 2021 - Elsevier
Efficient release and the delivery of active substances are necessary for diverse medical
applications including biosensors, biotechnology, and medical therapy. Meanwhile, drug …

Nanoparticle‐mediated drug delivery and gene therapy

S Jin, K Ye - Biotechnology progress, 2007 - Wiley Online Library
Biomedical application of nanotechnology is a rapidly developing area that raises new
prospect in the improvement of diagnosis and treatment of human diseases. The ability to …

Bioconjugated nanoparticles for DNA protection from cleavage

X He, K Wang, W Tan, B Liu, X Lin, C He… - Journal of the …, 2003 - ACS Publications
We have developed a novel method to protect DNA from cleavage using bioconjugated
nanoparticles. Positively charged amino-modified silica nanoparticles have been directly …

Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery

SB Hartono, NT Phuoc, M Yu, Z Jia… - Journal of Materials …, 2014 - pubs.rsc.org
Novel mesoporous silica nanoparticles (LPMSNs) functionalised with degradable poly (2-
dimethylaminoethyl acrylate)(PDMAEA) have been developed (PDMAEA–LPMSNs) as …

Design and application of magnetic-based theranostic nanoparticle systems

AS Wadajkar, JU Menon, T Kadapure… - Recent Patents on …, 2013 - ingentaconnect.com
Recently, magnetic-based theranostic nanoparticle (MBTN) systems have been studied,
researched, and applied extensively to detect and treat various diseases including cancer …

Efficacy of mesoporous silica nanoparticles in delivering BMP‐2 plasmid DNA for in vitro osteogenic stimulation of mesenchymal stem cells

TH Kim, M Kim, M Eltohamy, YR Yun… - … Research Part A, 2013 - Wiley Online Library
We report the ability of aminated mesoporous silica nanoparticles (MSN–NH2) with large
mesopore space and positive‐charged surface to deliver genes within rat mesenchymal …

Nanoparticle-mediated gene delivery

S Jin, JC Leach, K Ye - Micro and nano technologies in bioanalysis …, 2009 - Springer
Nonviral gene delivery has been gaining considerable attention recently. Although the
efficacy of DNA transfection, which is a major concern, is low in nonviral vector-mediated …

Plasmid DNA isolation using amino-silica coated magnetic nanoparticles (ASMNPs)

X He, H Huo, K Wang, W Tan, P Gong, J Ge - Talanta, 2007 - Elsevier
A simple and efficient approach for the rapid isolation of plasmid DNA from crude cell lysates
has been described. The approach took advantage of the amino-modified silica coated …

An antisense oligonucleotide carrier based on amino silica nanoparticles for antisense inhibition of cancer cells

J Peng, X He, K Wang, W Tan, H Li, X Xing… - … , Biology and Medicine, 2006 - Elsevier
Antisense oligonucleotides (anti-ODNs), which are able to interfere with gene expression at
the mRNA level, have potential activity in the treatment of viral infections or cancer …

Controlled size chitosan nanoparticles as an efficient, biocompatible oligonucleotides delivery system

R Manchanda, S Nimesh - Journal of applied polymer science, 2010 - Wiley Online Library
Polymeric nanoparticles of chitosan crosslinked with glutaraldehyde have been prepared
using reverse micellar system. An optically clear solution was obtained on redispersing …