In recent years, there has been a tremendous development of biotechnological,
pharmacological, and medical techniques which can be implemented in the functional …

In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Autoimmune pancreatitis (AIP) is a rare disease. The diagnosis of AIP is difficult and should
be made by a comprehensive evaluation of clinical, radiological, serological, and …

B cells orchestrate autoimmune responses in patients with systemic lupus erythematosus
(SLE), but broad-based B cell–directed therapies show only modest efficacy while blunting …

Systemic lupus erythematosus (SLE) is an autoimmune disorder that is characterized by
autoantibody production and dysregulated immune cell activation. Although the exact …

Treatment of systemic lupus erythematosus (SLE) currently employs agents with relatively
unselective immunosuppressive properties. However, two target-specific biological drugs …

Objective Dysregulated APRIL/BAFF signaling is implicated in the pathogenesis of multiple
autoimmune diseases, including systemic lupus erythematosus and lupus nephritis. We …

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with abnormal
activation of the immune system. Recent attention is increasing about how aberrant lipid and …

Despite belonging to a relatively new class of pharmaceuticals, biological drugs have been
used since the 1980s, when they brought about a breakthrough in the treatment of chronic …

Systemic lupus erythematosus (SLE), the prototype of systemic autoimmune diseases is
characterized by extreme heterogeneity with a variable clinical course. Renal involvement …