Viruses, friends, and foes: The case of Torque Teno Virus and the net state of immunosuppression

N Redondo, D Navarro, JM Aguado… - Transplant Infectious …, 2022 - Wiley Online Library
New reliable biomarkers are needed to improve individual risk assessment for post‐
transplant infection, acute graft rejection and other immune‐related complications after solid …

Torque teno virus load as marker of rejection and infection in solid organ transplantation–A systematic review and meta‐analysis

AL Van Rijn, R Roos, FW Dekker… - Reviews in Medical …, 2023 - Wiley Online Library
Balancing immunosuppression to prevent rejection in solid organ transplant (SOT)
recipients remains challenging. Torque teno virus (TTV), a commensal non‐pathogenic …

[HTML][HTML] Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients—a prospective observational trial

K Doberer, M Schiemann, R Strassl… - American Journal of …, 2020 - Elsevier
The nonpathogenic and ubiquitous torque teno virus (TTV) is associated with
immunosuppression in solid organ transplant recipients. Studies in kidney transplant …

The enigmatic roles of Anelloviridae and Redondoviridae in humans

LJ Taylor, EL Keeler, FD Bushman… - Current Opinion in …, 2022 - Elsevier
Anelloviridae and Redondoviridae are virus families with small, circular, single-stranded
DNA genomes that are common components of the human virome. Despite their small …

[HTML][HTML] Viral infections in HSCT: detection, monitoring, clinical management, and immunologic implications

C Annaloro, F Serpenti, G Saporiti, G Galassi… - Frontiers in …, 2021 - frontiersin.org
In spite of an increasing array of investigations, the relationships between viral infections
and allogeneic hematopoietic stem cell transplantation (HSCT) are still controversial, and …

Torque teno virus (TTV): a gentle spy virus of immune status, predictive marker of seroconversion to COVID‐19 vaccine in kidney and lung transplant recipients

P Roberto, L Cinti, A Napoli, D Paesani… - Journal of Medical …, 2023 - Wiley Online Library
To date, no comprehensive marker to monitor the immune status of patients is available.
Given that Torque teno virus (TTV), a known human virome component, has previously been …

Torque teno viruses in health and disease

B Webb, AGM Rakibuzzaman, S Ramamoorthy - Virus research, 2020 - Elsevier
Torque teno viruses (TTVs) are small, ubiquitous, viruses with a highly diverse, single-
stranded, negative sense DNA genome and wide host range. They are detected at high …

[HTML][HTML] High-density blood transcriptomics reveals precision immune signatures of SARS-CoV-2 infection in hospitalized individuals

JW Prokop, NL Hartog, D Chesla, W Faber… - Frontiers in …, 2021 - frontiersin.org
The immune response to COVID-19 infection is variable. How COVID-19 influences clinical
outcomes in hospitalized patients needs to be understood through readily obtainable …

[HTML][HTML] Torque teno virus loads after kidney transplantation predict allograft rejection but not viral infection

AL van Rijn, HF Wunderink, IA Sidorov… - Journal of Clinical …, 2021 - Elsevier
The main challenge of immunosuppressive therapy after solid organ transplantation is to
create a new immunological balance that prevents organ rejection and does not promote …

Torque‐teno virus for the prediction of graft rejection and infection disease after kidney transplantation: A systematic review and meta‐analysis

J Zeng, Y Tang, T Lin, T Song - Journal of Medical Virology, 2023 - Wiley Online Library
Torque teno virus (TTV) is a promising novel marker for quantifying the immune function in
solid organ recipients, whose diagnostic accuracy of acute rejection (AR) and infection after …