Promises of microbiome-based therapies

JS Bajaj, SC Ng, B Schnabl - Journal of hepatology, 2022 - Elsevier
Humans harbour large quantities of microbes, including bacteria, fungi, viruses and
archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota …

[HTML][HTML] Mediterranean diet and olive oil, microbiota, and obesity-related cancers. From mechanisms to prevention.

E Almanza-Aguilera, A Cano, M Gil-Lespinard… - Seminars in Cancer …, 2023 - Elsevier
Olive oil (OO) is the main source of added fat in the Mediterranean diet (MD). It is a mix of
bioactive compounds, including monounsaturated fatty acids, phytosterols, simple phenols …

Large-scale phage cultivation for commensal human gut bacteria

J Shen, J Zhang, L Mo, Y Li, Y Li, C Li, X Kuang… - Cell Host & Microbe, 2023 - cell.com
Phages are highly abundant in the human gut, yet most of them remain uncultured. Here, we
present a gut phage isolate collection (GPIC) containing 209 phages for 42 commensal …

Targeting nonalcoholic fatty liver disease via gut microbiome-centered therapies

M Koning, H Herrema, M Nieuwdorp… - Gut Microbes, 2023 - Taylor & Francis
Humans possess abundant amounts of microorganisms, including bacteria, fungi, viruses,
and archaea, in their gut. Patients with nonalcoholic fatty liver disease (NAFLD) exhibit …

[HTML][HTML] The resurgence of phage-based therapy in the era of increasing antibiotic resistance: from research progress to challenges and prospects

NJ Anyaegbunam, CC Anekpo… - Microbiological …, 2022 - Elsevier
Phage therapy was implemented almost a century ago but was subsequently abandoned
when antibiotics emerged. However, the rapid emergence of drug-resistant, which has …

[HTML][HTML] Gut microbiome in inflammatory bowel disease: Role in pathogenesis, dietary modulation, and colitis-associated colon cancer

J Gubatan, TL Boye, M Temby, RS Sojwal, DR Holman… - Microorganisms, 2022 - mdpi.com
The gut microbiome has increasingly been recognized as a critical and central factor in
inflammatory bowel disease (IBD). Here, we review specific microorganisms that have been …

[HTML][HTML] Future modulation of gut microbiota: from eubiotics to FMT, engineered bacteria, and phage therapy

C Airola, A Severino, S Porcari, W Fusco, BH Mullish… - Antibiotics, 2023 - mdpi.com
The human gut is inhabited by a multitude of bacteria, yeasts, and viruses. A dynamic
balance among these microorganisms is associated with the well-being of the human being …

[HTML][HTML] Effect of the probiotic strain, Lactiplantibacillus plantarum P9, on chronic constipation: A randomized, double-blind, placebo-controlled study

T Ma, N Yang, Y Xie, Y Li, Q Xiao, Q Li, H Jin… - Pharmacological …, 2023 - Elsevier
Chronic constipation (CC) is a common gastrointestinal condition associated with intestinal
inflammation, and the condition considerably impairs patients' quality of life. We conducted a …

Dynamic network modeling of gut microbiota during Alzheimer's disease progression in mice

Y Li, Y Chen, Y Fan, Y Chen, Y Chen - Gut Microbes, 2023 - Taylor & Francis
The intimate association between the gut microbiota (GM) and the central nervous system
points to potential intervention strategies for neurological diseases. Nevertheless, there is …

A critical review of novel antibiotic resistance prevention approaches with a focus on postbiotics

MA Ozma, SR Moaddab, H Hosseini… - Critical reviews in …, 2023 - Taylor & Francis
Antibiotic resistance is a significant public health issue, causing illnesses that were once
easily treatable with antibiotics to develop into dangerous infections, leading to substantial …