Rationale A great deal of research supports the role of nicotine in cigarette addiction.
However, the effectiveness of nicotine replacement therapy (NRT) as a smoking cessation …

Recent reports suggest that nicotine withdrawal symptoms are common among adolescents
after a few weeks of intermittent tobacco use. No current model of nicotine dependence had …

Objective To examine a potential association between biologically confirmed secondhand
smoke exposure and symptoms ofDiagnostic and Statistical Manual of Mental Disorders …

Background: In Canada, low awareness of evidence-based interventions for the clinical
management of alcohol use disorder exists among health care providers and people who …

The present study provides the first direct molecular genetics support for Gray's
Reinforcement Sensitivity Theory (RST), which is one of the most influential biologically …

Background: Mounting evidence has revealed an inverse association between cigarette
smoking and the risk of Parkinson's disease (PD). Meanwhile, cigarette smoking has been …

A major obstacle to the development of medications for nicotine dependence is the lack of
animal and human laboratory models with sufficient predictive clinical validity to support the …

In most contemporary theories of emotion, the processes of desire, happiness, and pleasure
are separable yet affect each other. Desire reflects the focused interest in a goal object and …

Objective: To evaluate the association between secondhand smoke (SHS) exposure and
depression. Tobacco smoking and depression are strongly associated, but the possible …

Drugs of abuse, including, nicotine have been shown to enhance brain reward functions in
the mesocortico-limbic dopamine (DA) system in general, and the nucleus accumbens in …