[HTML][HTML] Current and future trends on diagnosis and prognosis of glioblastoma: from molecular biology to proteomics

AS Silantyev, L Falzone, M Libra, OI Gurina… - Cells, 2019 - mdpi.com
Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

[HTML][HTML] Artificial intelligence in the management of glioma: era of personalized medicine

H Sotoudeh, O Shafaat, JD Bernstock… - Frontiers in …, 2019 - frontiersin.org
Purpose: Artificial intelligence (AI) has accelerated novel discoveries across multiple
disciplines including medicine. Clinical medicine suffers from a lack of AI-based …

Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma

KV Keu, TH Witney, S Yaghoubi, J Rosenberg… - Science translational …, 2017 - science.org
High-grade gliomas are aggressive cancers that often become rapidly fatal. Immunotherapy
using CD8+ cytotoxic T lymphocytes (CTLs), engineered to express both herpes simplex …

Changes in tissue fluidity predict tumor aggressiveness in vivo

F Sauer, S Grosser, M Shahryari, A Hayn… - Advanced …, 2023 - Wiley Online Library
Cancer progression is caused by genetic changes and associated with various alterations in
cell properties, which also affect a tumor's mechanical state. While an increased stiffness …

[HTML][HTML] Liquid biopsy in glioblastoma

L Ronvaux, M Riva, A Coosemans, M Herzog… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma is the most common and malignant primary brain tumor.
Despite intensive research for new treatments, the survival of patients has not significantly …

Importance of the intersection of age and sex to understand variation in incidence and survival for primary malignant gliomas

GM Wang, G Cioffi, N Patil, KA Waite, R Lanese… - Neuro …, 2022 - academic.oup.com
Background Gliomas are the most common type of malignant brain and other CNS tumors,
accounting for 80.8% of malignant primary brain and CNS tumors. They cause significant …

Epidemiology and diagnosis of brain tumors

NA Butowski - CONTINUUM: Lifelong Learning in Neurology, 2015 - journals.lww.com
Abstract Purpose of Review: Brain tumors consist of a collection of neoplasms arising from
within the brain or from systemic tumors that have metastasized to the brain. This article …

[HTML][HTML] The role of translocator protein TSPO in hallmarks of glioblastoma

LM Ammer, A Vollmann-Zwerenz, V Ruf, CH Wetzel… - Cancers, 2020 - mdpi.com
Simple Summary The translocator protein (TSPO) has been under extensive investigation as
a specific marker in positron emission tomography (PET) to visualize brain lesions following …

[HTML][HTML] Nanogels as a versatile drug delivery system for brain cancer

B Stawicki, T Schacher, H Cho - Gels, 2021 - mdpi.com
Chemotherapy and radiation remain as mainstays in the treatment of a variety of cancers
globally, yet some therapies exhibit limited specificity and result in harsh side effects in …

[HTML][HTML] Insights into molecular therapy of glioma: current challenges and next generation blueprint

Y Rajesh, I Pal, P Banik, S Chakraborty… - Acta pharmacologica …, 2017 - nature.com
Glioma accounts for the majority of human brain tumors. With prevailing treatment regimens,
the patients have poor survival rates. In spite of current development in mainstream glioma …