The endothelium, a tissue that forms a single layer of cells lining various organs and cavities
of the body, especially the heart and blood as well as lymphatic vessels, plays a complex …

Traditionally, non-cancer diseases are not considered as health risks following exposure to
low doses of ionizing radiation. Indeed, non-cancer diseases are classified as deterministic …

The integrity of the endothelial lining of the vasculature is essential for vascular homeostasis
and normal organ function. Endothelial injury or dysfunction has been implicated in the …

Chronic inflammation and disordered lipid metabolism represent hallmarks of
atherosclerosis. Considerable evidence suggests that innate immune defense mechanisms …

Large-scale gene expression studies provide significant insight into genes differentially
regulated in disease processes such as cancer. However, these investigations offer limited …

Mice are widely used to study arterial disease in humans, and the pathogenesis of arterial
diseases is known to be strongly influenced by hemodynamic factors. It is, therefore, of …

In humans, apolipoprotein E (apoE) is a polymorphic multifunctional protein. 1 It is coded by
three alleles (2, 3, 4) of a modulator gene (level, variability, and susceptibility gene) at the …

The specific profile of estrogens on cardiovascular risk, with limiting action on atherogenesis
but a less clear protection on cardiovascular episodes, might be improved by other agonists …

Large-scale epidemiological studies have revealed a strong association between
hypertriglyceridemia and coronary arteriosclerotic disease. However, there are conflicting …

Role of oxidized LDL in atherosclerosis Page 66 Chapter 3 Role of Oxidized LDL in
Atherosclerosis E. Leiva, S. Wehinger, L. Guzmán and R. Orrego Additional information is …