With advancing age, the cerebral vasculature becomes dysfunctional, and this dysfunction is
associated with cognitive decline. However, the initiating cause of these age-related …

A high-fat choline diet (HFCD)-induced atherosclerosis model in ApoE−/− mice was
established to explore the anti-atherosclerotic effects of gypenoside XLIX (GPE). It was …

A large number of previous reports have focused on the transport of amyloid-β peptides
through cerebral endothelial cells via the blood–brain barrier, while fewer reports have …

Liver X receptor (LXR), a sterol-activated nuclear hormone receptor, has been implicated in
cholesterol and fatty acid homeostasis via regulation of reverse cholesterol transport and de …

Atherosclerosis is a chronic inflammatory disease of the arteries that is characterised by the
activation of endothelial cells, the recruitment of monocytes into the vessel wall and the …

Although in apoE/LDLR−/− mice atherosclerotic plaques develop spontaneously, various
atherogenic diets (eg Western diet) are frequently used to accelerate the disease in this …

Acute thrombosis secondary to atherosclerotic plaque rupture is the main cause of acute
cardiac and cerebral ischemia. An animal model of unstable atherosclerotic plaques is …

Easy access to high-calorie and fat-dense fast food has resulted in unhealthy dietary and
lifestyle changes worldwide, which affects both developed and developing economies. This …

Background Two mutants of apolipoprotein (apo) A‐I, V156K and A158E, showed markedly
different structural and functional properties in lipid‐free and lipid‐bound states in the …

The present study investigated the effects of exercise training on arterial pressure, baroreflex
sensitivity, cardiovascular autonomic control and metabolic parameters on female LDL …